Digestion of diacylglycerols by extracellular PTL:colipase

Stable Identifier
Reaction [transition]
Homo sapiens
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Pancreatic lipase catalyzes the hydrolysis of extracellular dicylglycerols to yield monoacylglycerols and long-chain fatty acids. The enzyme is active only when complexed with colipase protein and plays a major role in the digestion of dietary diacylglycerols in the small intestine (Carriere et al. 2000; Giller et al. 1992).

Literature References
PubMed ID Title Journal Year
1379598 Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity.

Buchwald, P, Giller, T, Hunziker, W, Blum-Kaelin, D

J Biol Chem 1992
11040182 The specific activities of human digestive lipases measured from the in vivo and in vitro lipolysis of test meals

Ferrato, F, De Caro, J, Verger, R, Laugier, R, Renou, C, Lopez, V, Lengsfeld, H, Carriere, F, De Caro, A

Gastroenterology 2000
Catalyst Activity

acylglycerol lipase activity of PNLIP:CLPS [extracellular region]

Orthologous Events
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