Digestion of triacylglycerols by extracellular PTL:colipase

Stable Identifier
R-HSA-192422
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Pancreatic lipase catalyzes the hydrolysis of extracellular triacylglycerols to yield diacylglycerols and long-chain fatty acids. The enzyme is active only when complexed with colipase protein and plays a major role in the digestion of dietary triacylglycerols in the small intestine (Carriere et al. 2000; Giller et al. 1992).

Literature References
PubMed ID Title Journal Year
11040182 The specific activities of human digestive lipases measured from the in vivo and in vitro lipolysis of test meals

Carriere, F, Renou, C, Lopez, V, De Caro, J, Ferrato, F, Lengsfeld, H, De Caro, A, Laugier, R, Verger, R

Gastroenterology 2000
1379598 Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity.

Giller, T, Buchwald, P, Blum-Kaelin, D, Hunziker, W

J Biol Chem 1992
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
acylglycerol lipase activity of PNLIP:CLPS [extracellular region]
Physical Entity
Activity
Orthologous Events
Authored
Created
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