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Nuclear export of snRNA transcripts
Stable Identifier
R-HSA-191825
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism of RNA (Homo sapiens)
Metabolism of non-coding RNA (Homo sapiens)
snRNP Assembly (Homo sapiens)
Nuclear export of snRNA transcripts (Homo sapiens)
General
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The snRNAs, except U6 snRNA, are transcribed by RNA polymerase II, co-transcriptionally capped and exported rapidly to the cytoplasm in association with a cap-binding complex and the export factor PHAX.
Literature References
PubMed ID
Title
Journal
Year
11333016
The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export
Segref, A
,
Ohno, M
,
Mattaj, IW
RNA
2001
Participants
Input
m7G capped snRNA:CBC:PHAX complex [nucleoplasm]
(Homo sapiens)
Output
Cap Binding Complex (CBC) [cytosol]
(Homo sapiens)
m7G capped Spliceosomal snRNA [cytosol]
(Homo sapiens)
PHAX [cytosol]
(Homo sapiens)
Participates
as an event of
snRNP Assembly (Homo sapiens)
Event Information
Go Biological Process
nuclear export (0051168)
This event is regulated
Requirements
Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
Authored
Gillespie, ME (2007-01-30)
Reviewed
Luhrmann, R (2007-04-30)
Created
Gillespie, ME (2007-01-25)
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