snRNP complex assembly

Stable Identifier
R-HSA-191786
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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To facilitate snRNP assembly, the SMN complex must bring together the Sm proteins and an Sm-site-containing snRNA. The SMN:Sm protein complex binds to the m7G capped snRNAs in the cytoplasm.

Literature References
PubMed ID Title Journal Year
12441251 SMN-mediated assembly of RNPs: a complex story

Meister, G, Eggert, C, Fischer, U

Trends Cell Biol 2002
9845364 A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing

Pellizzoni, L, Kataoka, N, Charroux, B, Dreyfuss, G

Cell 1998
10556282 Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy

Buhler, D, Raker, V, Luhrmann, R, Fischer, U

Hum Mol Genet 1999
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