Reactome | PMVK [cytosol]

PMVK [cytosol]

Stable Identifier

R-HSA-191348

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Phosphomevalonate kinase

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15126 PMVK

Gene Names

PMVK, PMKI

Chain

chain:1-192

Reference Genes

BioGPS Gene:10654 PMVK

COSMIC (genes):PMVK PMVK

CTD Gene:10654 PMVK

dbSNP Gene:10654 PMVK

ENSEMBL:ENSG00000163344 PMVK

HGNC:9141 PMVK

KEGG:hsa:10654 PMVK

Monarch:10654 PMVK

NCBI Gene:10654 PMVK

OMIM:607622 PMVK

UCSC:Q15126 PMVK

Reference Transcript

RefSeq:NM_006556.3 PMVK

Other Identifiers

10654

11730547_a_at

11754085_a_at

11756161_x_at

16693864

203515_PM_s_at

203515_s_at

2436921

2436922

2436923

2436924

2436925

2436926

2436927

2436932

2436933

2436934

35621_at

7920567

A_23_P114774

GE57796

GO:0003824

GO:0004631

GO:0005515

GO:0005524

GO:0005737

GO:0005777

GO:0005829

GO:0006629

GO:0006695

GO:0006790

GO:0016020

GO:0016126

GO:0016301

GO:0016740

GO:0019287

GO:0043226

GO:0055086

GO:0070062

GO:0070723

GO:1901135

ILMN_1715896

L77213_at

PH_hs_0002641

TC01003297.hg

g5729979_3p_s_at

Participates

as an output of

Expression of Phosphomevalonate Kinase (PMVK) (Homo sapiens)

Inferred To

PMVK [cytosol] (Bos taurus)

PMVK [cytosol] (Caenorhabditis elegans)

PMVK [cytosol] (Canis familiaris)

PMVK [cytosol] (Danio rerio)

PMVK [cytosol] (Drosophila melanogaster)

PMVK [cytosol] (Gallus gallus)

PMVK [cytosol] (Mus musculus)

PMVK [cytosol] (Rattus norvegicus)

PMVK [cytosol] (Sus scrofa)

Cross References

Guide to Pharmacology - Targets

641

ENSEMBL

ENSP00000357452, ENSG00000163344, ENST00000368467

OpenTargets

ENSG00000163344

GeneCards

PMVK

HPA

ENSG00000163344-PMVK

PRO

Q15126

Pharos - Targets

Q15126

Orphanet

PMVK

HMDB Protein

HMDBP01017

PDB

3CH4

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96D03 DDT4L			0.556	3
UniProt:Q13360-2 ZNF177			0.556	3
UniProt:Q17RF5 ODAPH			0.527	2
UniProt:Q8N6S5 AR6P6			0.527	2
UniProt:Q9BWG6 SCNM1			0.527	2
UniProt:P29084 GTF2E2	1	GTF2E2 [nucleoplasm] (R-HSA-65563)	0.527	2
UniProt:P01160 NPPA	5	NPPA(124-151) [extracellular region] (R-HSA-5578799) NPPA(1-151) [extracellular region] (R-HSA-976950) NPPA(1-25) [extracellular region] (R-HSA-5578791) NPPA(56-123) [extracellular region] (R-HSA-5578797) NPPA(26-55) [extracellular region] (R-HSA-5578794)	0.527	2
UniProt:P02675 FGB	5	FGB [extracellular region] (R-HSA-140584) FGB(31-44) [extracellular region] (R-HSA-140876) FGB [plasma membrane] (R-HSA-140917) FGB(31-491) [extracellular region] (R-HSA-140846) FGB(31-491) [platelet alpha granule lumen] (R-HSA-140921)	0.527	2
UniProt:Q9H2D1 SLC25A32	1	SLC25A32 [mitochondrial inner membrane] (R-HSA-200645)	0.527	2
UniProt:Q8WVK2 SNRNP27	1	SNRNP27 [nucleoplasm] (R-HSA-6806778)	0.527	2

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