MIR181C microRNA binds 3'UTR of NOTCH4 mRNA

Stable Identifier
R-HSA-1912364
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
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MIR181C microRNA binds 3'UTR of NOTCH4 mRNA
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miR-181C microRNA inhibits translation of NOTCH4 mRNA by binding to its 3'UTR. miR181c is a candidate tumor suppressor in gastric cancer.

Literature References
PubMed ID Title Journal Year
20080834 Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis

Hashimoto, Y, Akiyama, Y, Otsubo, T, Shimada, S, Yuasa, Y

Carcinogenesis 2010
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
negative regulation of gene expression (0010629)
Authored
Egan, SE  (2011-11-14)
Orlic-Milacic, M  (2011-11-14)
Reviewed
Haw, R  (2012-02-06)
Created
Orlic-Milacic, M  (2011-11-02)