ITCH ubiquitinates DTX

Stable Identifier
R-HSA-1912357
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
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ITCH ubiquitinates DTX, targeting it for degradation.

Literature References
PubMed ID Title Journal Year
17028573 Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains

Chastagner, P, Israel, A, Brou, C

EMBO Rep 2006
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ubiquitin-protein transferase activity of DTX:ITCH [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created