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Ub-DLL/JAG:NOTCH1 fragment [plasma membrane]
Stable Identifier
R-HSA-1911540
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
NOTCH1 fragment:Ub-DSL
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by NOTCH1 in Cancer (Homo sapiens)
Signaling by NOTCH1 PEST Domain Mutants in Cancer (Homo sapiens)
Constitutive Signaling by NOTCH1 PEST Domain Mutants (Homo sapiens)
ADAM10/17 cleaves ligand-bound NOTCH1 PEST domain mutants to produce NEXT1 PEST domain mutants (Homo sapiens)
Ub-DLL/JAG:NOTCH1 fragment [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH1 (Homo sapiens)
Activated NOTCH1 Transmits Signal to the Nucleus (Homo sapiens)
Complex of NOTCH1 with its ligand is cleaved to produce NEXT1 (Homo sapiens)
Ub-DLL/JAG:NOTCH1 fragment [plasma membrane] (Homo sapiens)
Participants
components
NOTCH1 fragment:DLL/JAG [plasma membrane]
(Homo sapiens)
Ub [cytosol]
(Homo sapiens)
Participates
as an output of
ADAM10/17 cleaves ligand-bound NOTCH1 PEST domain mutants to produce NEXT1 PEST domain mutants (Homo sapiens)
Complex of NOTCH1 with its ligand is cleaved to produce NEXT1 (Homo sapiens)
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