Reactome | maltose + H2O => 2 D-glucose (sucrase-isomaltase)

maltose + H2O => 2 D-glucose (sucrase-isomaltase)

Stable Identifier

R-HSA-191108

Type

Reaction [transition]

Species

Homo sapiens

Compartment

extracellular region, plasma membrane

Synonyms

Digestion of maltose by sucrase-isomaltase to yield glucose

ReviewStatus

5/5

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maltose + H2O => 2 D-glucose (sucrase-isomaltase)

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The alpha-1,4 linkages of extracellular maltose are hydrolyzed to yield glucose in a reaction catalyzed by sucrase-maltase (Nichols et al. 1998). In the body, this enzyme is found as a dimer on the external face of enterocytes in microvilli of the small intestine (Hauri et al. 1985), and acts on maltose derived directly from the diet and from the hydrolysis of starch.

Literature References

PubMed ID	Title	Journal	Year
3897250	Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells Hauri, HP, Fransen, JA, Bienz, D, Marxer, A, Sterchi, EE	J Cell Biol	1985
12547908	The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities Swallow, DM, Sterchi, EE, Hahn, D, Sen, P, Nichols, BL, Avery, S	Proc Natl Acad Sci U S A	2003