Synthesis of Cx43

Stable Identifier
R-HSA-191072
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Cx proteins are cotranslationally inserted into ER membranes in an SRP (signal recognition particle)-dependent process (Falk et al., 1994).

It has been observed, however, that the oligomerization of Cx43 into connexons does not occur before the Trans-Golgi network (Musil and Goodenough, 1993; Koval, 2006).

Literature References
PubMed ID Title Journal Year
15536180 Presence of functional gap junctions in human embryonic stem cells

Wong, RC, Pebay, A, Nguyen, LT, Koh, KL, Pera, MF

Stem Cells 2004
Participants
Participant Of
Orthologous Events
Authored
Created
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