Reactome | Connexin oligomerization in endoplasmic reticulum membrane

Connexin oligomerization in endoplasmic reticulum membrane

Stable Identifier

R-HSA-190681

Type

Reaction [transition]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

ReviewStatus

5/5

Locations in the PathwayBrowser

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Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Gap junction trafficking and regulation (Homo sapiens)
    - Gap junction trafficking (Homo sapiens)
      - Gap junction assembly (Homo sapiens)
        
        Oligomerization of connexins into connexons (Homo sapiens)
        
        Connexin oligomerization in endoplasmic reticulum membrane (Homo sapiens)

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Connexin oligomerization in endoplasmic reticulum membrane

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Studies using microsomes have revealed that oligomerization of connexins Cx26, Cx43, and Cx32 can occur after insertion of connexins in the ER membrane (Falk et al. 1997; Ahmad et al. 1999, Ahmad and Evans, 2002).

Literature References

PubMed ID	Title	Journal	Year
9184217	Cell-free synthesis and assembly of connexins into functional gap junction membrane channels Kumar, NM, Gilula, NB, Falk, MM, Buehler, LK	EMBO J	1997