Reactome | Activated FGFR [plasma membrane]

Activated FGFR

Stable Identifier

R-HSA-190352

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by Insulin receptor (Homo sapiens)
    - Insulin receptor signalling cascade (Homo sapiens)
      - IRS-mediated signalling (Homo sapiens)
        
        PI3K Cascade (Homo sapiens)
        
        PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
        
        PI3K-containing complexes [plasma membrane, cytosol, endosome membrane] (Homo sapiens)
        
        Activated FGFR bound to PI3K [plasma membrane] (Homo sapiens)
        
        GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Homo sapiens)
        
        Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Homo sapiens)
        
        Activated FGFR:p-FRS2 [plasma membrane] (Homo sapiens)
        
        Activated FGFR [plasma membrane] (Homo sapiens)
  - Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)
    - IGF1R signaling cascade (Homo sapiens)
      - IRS-related events triggered by IGF1R (Homo sapiens)
        
        IRS-mediated signalling (Homo sapiens)
        
        PI3K Cascade (Homo sapiens)
        
        PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
        
        PI3K-containing complexes [plasma membrane, cytosol, endosome membrane] (Homo sapiens)
        
        Activated FGFR bound to PI3K [plasma membrane] (Homo sapiens)
        
        GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Homo sapiens)
        
        Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Homo sapiens)
        
        Activated FGFR:p-FRS2 [plasma membrane] (Homo sapiens)
        
        Activated FGFR [plasma membrane] (Homo sapiens)

Participants

members

Participant Of

hasComponent

Activated FGFR:p-FRS2 [plasma membrane]

Inferred To

Activated FGFR [plasma membrane] (Bos taurus)

Activated FGFR [plasma membrane] (Canis familiaris)

Activated FGFR [plasma membrane] (Danio rerio)

Activated FGFR [plasma membrane] (Drosophila melanogaster)

Activated FGFR [plasma membrane] (Gallus gallus)

Activated FGFR [plasma membrane] (Mus musculus)

Activated FGFR [plasma membrane] (Rattus norvegicus)

Activated FGFR [plasma membrane] (Sus scrofa)

Activated FGFR [plasma membrane] (Taeniopygia guttata)

Activated FGFR [plasma membrane] (Xenopus tropicalis)