HMBL spontaneously transforms to URO1

Stable Identifier
R-HSA-190168
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
hydroxymethylbilane => H2O + uroporphyrinogen I, Spontaneous conversion of HMBL to uroporphyrinogen I (URO1)
ReviewStatus
5/5
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HMBL spontaneously transforms to URO1
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Hydroxymethybilane (HMBL) can spontaneously cyclize and rearrange to form uroporphyrinogen I (URO1).
Literature References
PubMed ID Title Journal Year
3805019 Purification and properties of uroporphyrinogen III synthase from human erythrocytes

Tsai, SF, Bishop, DF, Desnick, RJ

J Biol Chem 1987
Participants
Input
Output
Participates
as an event of
Orthologous Events
hydroxymethylbilane => uroporphyrinogen I + H2O (Gallus gallus)
Authored
Jassal, B  (2007-01-24)
D'Eustachio, P  (2007-01-24)
Reviewed
Sassa, S  (2007-01-24)
Created
Jassal, B  (2006-12-18)
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