Reactome | PPOX [mitochondrial intermembrane space]

PPOX [mitochondrial intermembrane space]

Stable Identifier

R-HSA-189434

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial intermembrane space

Synonyms

Protoporphyrinogen oxidase, PPOX_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P50336 PPOX

Gene Names

PPOX

Chain

chain:1-477

Reference Genes

BioGPS Gene:5498 PPOX

COSMIC (genes):PPOX PPOX

CTD Gene:5498 PPOX

dbSNP Gene:5498 PPOX

ENSEMBL:ENSG00000143224 PPOX

HGNC:9280 PPOX

KEGG Gene (Homo sapiens):5498 PPOX

Monarch:5498 PPOX

NCBI Gene:5498 PPOX

OMIM:600923 PPOX

UCSC:P50336 PPOX

Reference Transcript

Other Identifiers

0006350348

11722711_a_at

11722712_x_at

16672779

204788_s_at

2363485

2363486

2363488

2363490

2363492

2363494

2363496

2363498

2363499

2363501

2363502

2363504

2363506

2363508

2363509

2363511

2363512

2363513

37098_at

5498

7906688

A_23_P201400

A_24_P102726

D38537_s_at

GE79427

GO:0003674

GO:0004729

GO:0005575

GO:0005622

GO:0005737

GO:0005739

GO:0005743

GO:0005758

GO:0006779

GO:0006782

GO:0006783

GO:0008150

GO:0009058

GO:0016020

GO:0016491

GO:0031304

GO:0031305

GO:0031966

GO:0034641

GO:0042493

GO:0043167

GO:0043226

GO:0046501

GO:0050660

GO:0055114

HMNXSV003038664

HMNXSV003041228

ILMN_1673798

PH_hs_0018309

g4506000_3p_a_at

Participates

as a component of

2xPPOX:FAD [mitochondrial intermembrane space] (Homo sapiens)

Inferred To

HEM14 [mitochondrial intermembrane space] (Saccharomyces cerevisiae)

Ppox [mitochondrial intermembrane space] (Drosophila melanogaster)

Ppox [mitochondrial intermembrane space] (Mus musculus)

Ppox [mitochondrial intermembrane space] (Rattus norvegicus)

PPOX [mitochondrial intermembrane space] (Bos taurus)

PPOX [mitochondrial intermembrane space] (Canis familiaris)

PPOX [mitochondrial intermembrane space] (Plasmodium falciparum)

PPOX [mitochondrial intermembrane space] (Sus scrofa)

hem14 [mitochondrial intermembrane space] (Schizosaccharomyces pombe)

ppox [mitochondrial intermembrane space] (Danio rerio)

ppox [mitochondrial intermembrane space] (Dictyostelium discoideum)

Cross References

RefSeq

NP_000300.1, NP_001116236.1

OpenTargets

ENSG00000143224

ZINC - Substances

PPOX_HUMAN

ZINC - Biogenic

PPOX_HUMAN

ZINC target

P50336

PRO

P50336

PDB

4IVM, 3NKS, 4IVO

ZINC - Metabolites

PPOX_HUMAN

IntEnz

1.3.3.4

HPA

ENSG00000143224-PPOX

GeneCards

P50336

Ensembl

ENSP00000356978, ENSP00000343943, ENST00000352210, ENST00000367999, ENSG00000143224

Pharos - Targets

P50336

Orphanet

15130

ZINC - Predictions - Purchasable

PPOX_HUMAN

HMDB Protein

HMDBP01021