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HMOX1 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-189395
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Heme oxygenase 1, HO1_HUMAN
Icon
Locations in the PathwayBrowser for interactor UniProt:Q9NYP7 ELOVL5
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
Expression of HMOX1 (Homo sapiens)
HMOX1 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09601 HMOX1
Gene Names
HMOX1, HO, HO1
Chain
chain:1-288, chain:1-265
Reference Genes
BioGPS Gene:3162 HMOX1
COSMIC (genes):HMOX1 HMOX1
CTD Gene:3162 HMOX1
dbSNP Gene:3162 HMOX1
ENSEMBL:ENSG00000100292 HMOX1
ENSEMBL_homo_sapiens_GENE:ENSG00000100292.18 HMOX1
HGNC:5013 HMOX1
KEGG Gene (Homo sapiens):3162 HMOX1
Monarch:3162 HMOX1
NCBI Gene:3162 HMOX1
OMIM:141250 HMOX1
Reference Transcript
RefSeq:NM_002133.2 HMOX1
Other Identifiers
11716939_a_at
11753445_a_at
11753446_x_at
16929562
203665_PM_at
203665_at
3162
33802_at
3944138
3944139
3944140
3944141
3944142
3944144
3944145
3944146
8072678
A_23_P120883
GE61857
GO:0001525
GO:0001935
GO:0002246
GO:0002376
GO:0002686
GO:0003012
GO:0003824
GO:0004392
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005739
GO:0005741
GO:0005783
GO:0005789
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006788
GO:0006879
GO:0006914
GO:0006915
GO:0006954
GO:0006979
GO:0012501
GO:0014806
GO:0016020
GO:0016236
GO:0016239
GO:0016242
GO:0016491
GO:0019899
GO:0020037
GO:0023052
GO:0032722
GO:0034101
GO:0034383
GO:0034605
GO:0035094
GO:0035556
GO:0042060
GO:0042167
GO:0042168
GO:0042542
GO:0042802
GO:0042803
GO:0043123
GO:0043226
GO:0045765
GO:0045766
GO:0046872
GO:0048471
GO:0048661
GO:0048662
GO:0048856
GO:0048870
GO:0055065
GO:0060586
GO:0071243
GO:0071276
GO:0071456
GO:0072719
GO:0090050
GO:1902042
GO:1903589
GO:1904019
GO:1904037
HMNXSV003008800
ILMN_1800512
PH_hs_0011943
TC22000259.hg
TC22001089.hg
X06985_at
g4504436_3p_at
p33878
Participates
as a member of
Tail-anchored proteins [endoplasmic reticulum membrane] (Homo sapiens)
as an output of
Expression of HMOX1 (Homo sapiens)
as a component of
HMOX1 dimer [endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
HMOX1 [nucleoplasm]
HMOX1 [mitochondrial outer membrane]
HMOX1 [cytosol]
Inferred To
hmox1 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
HMOX1 [endoplasmic reticulum membrane]
(Bos taurus)
HMOX1 [endoplasmic reticulum membrane]
(Canis familiaris)
HMOX1 [endoplasmic reticulum membrane]
(Danio rerio)
HMOX1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
HMOX1 [endoplasmic reticulum membrane]
(Gallus gallus)
HMOX1 [endoplasmic reticulum membrane]
(Mus musculus)
HMOX1 [endoplasmic reticulum membrane]
(Rattus norvegicus)
HMOX1 [endoplasmic reticulum membrane]
(Sus scrofa)
Cross References
RefSeq
NP_002124.1
Guide to Pharmacology - Targets
1441
OpenTargets
ENSG00000100292
ZINC - Substances
HMOX1_HUMAN
ZINC target
P09601
PRO
P09601
PDB
3HOK
,
1OZL
,
1OZE
,
1NI6
,
5BTQ
,
1T5P
,
1S8C
,
1N45
,
1XK3
,
1XK2
,
3TGM
,
1XK1
,
6EHA
,
1TWR
,
1N3U
,
1XJZ
,
4WD4
,
1XK0
,
3CZY
,
1OZW
,
1OZR
,
1OYK
,
1TWN
,
1OYL
,
1S13
,
3K4F
GeneCards
P09601
HPA
ENSG00000100292-HMOX1
Ensembl
ENSP00000216117
,
ENST00000216117
,
ENSG00000100292
Pharos - Targets
P09601
ZINC - Predictions - Purchasable
HMOX1_HUMAN
Orphanet
24601
HMDB Protein
HMDBP00198
Interactors (34)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC3 3a
9
O-glycosyl 3a [virion membrane]
(R-COV-9694395)
O-glycosyl 3a [endocytic vesicle membrane]
(R-COV-9694729)
O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694386)
GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9694658)
3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9694716)
3a [endoplasmic reticulum lumen]
(R-COV-9694584)
O-glycosyl 3a [endolysosome membrane]
(R-COV-9754541)
O-glycosyl 3a [plasma membrane]
(R-COV-9694433)
O-glycosyl 3a [extracellular region]
(R-COV-9694387)
0.738
4
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.601
4
UniProt:P11912 CD79A
2
p-Y188,Y199-CD79A [plasma membrane]
(R-HSA-983539)
CD79A [plasma membrane]
(R-HSA-197154)
0.556
3
UniProt:Q96KR6 F210B
0.556
3
UniProt:Q8TBP5 F174A
0.556
3
UniProt:Q8TDT2 GP152
0.556
3
UniProt:P49447 CY561
0.556
3
UniProt:Q13113 PDZ1I
0.556
3
UniProt:Q9NUH8 TM14B
0.556
3
UniProt:Q9Y282 ERGI3
0.556
3
UniProt:O60669 SLC16A7
1
SLC16A7 [plasma membrane]
(R-HSA-373955)
0.556
3
UniProt:Q9BUF7-2 CRB3
0.556
3
UniProt:Q9BY50 SEC11C
1
SEC11C [endoplasmic reticulum membrane]
(R-HSA-265065)
0.556
3
UniProt:Q96MV1 TLCD4
0.556
3
UniProt:Q7Z7G2 CPLX4
0.556
3
UniProt:Q5JX71 F209A
0.556
3
UniProt:Q9GZR5 ELOVL4
1
ELOVL4 [endoplasmic reticulum membrane]
(R-HSA-548705)
0.556
3
UniProt:Q8N5M9 JAGN1
0.556
3
IntAct:EBI-22344578 CCSB ORF ID
0.556
3
UniProt:O75208 COQ9
1
COQ9 [mitochondrial inner membrane]
(R-HSA-8932994)
0.556
3
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.556
3
UniProt:Q96DZ7 T4S19
0.556
3
UniProt:Q53TN4 CYBRD1
1
CYBRD1 [plasma membrane]
(R-HSA-917788)
0.556
3
UniProt:Q9NYP7 ELOVL5
1
ELOVL5 [endoplasmic reticulum membrane]
(R-HSA-548679)
0.556
3
UniProt:Q15800 MSMO1
1
MSMO1 [endoplasmic reticulum membrane]
(R-HSA-194648)
0.556
3
UniProt:Q9H5J4 ELOVL6
1
ELOVL6 [endoplasmic reticulum membrane]
(R-HSA-548680)
0.556
3
UniProt:Q3SXY8 ARL13B
8
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
ARL13B [plasma membrane]
(R-HSA-9716787)
0.556
3
UniProt:Q9Y6I9 TEX264
2
TEX264 [extracellular region]
(R-HSA-8863002)
TEX264 [platelet alpha granule lumen]
(R-HSA-8863000)
0.527
3
UniProt:Q9BZ11 ADAM33
1
ADAM33 [plasma membrane]
(R-HSA-708324)
0.527
2
UniProt:Q9P296 C5AR2
1
C5AR2 [plasma membrane]
(R-HSA-964798)
0.527
2
UniProt:Q9NU19 TB22B
0.527
2
UniProt:Q16880 UGT8
1
UGT8 [endoplasmic reticulum membrane]
(R-HSA-9844570)
0.527
3
UniProt:Q9Y5M8 SRPRB
1
SRPRB [endoplasmic reticulum membrane]
(R-HSA-265002)
0.527
2
UniProt:Q9NUX5 POT1
1
POT1 [nucleoplasm]
(R-HSA-174890)
0.508
2
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