BIL translocates from the cytosol to the ER lumen

Stable Identifier
R-HSA-189381
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol, endoplasmic reticulum lumen
ReviewStatus
5/5
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BIL translocates from the cytosol to the ER lumen
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The enzyme which catalyzes the conjugation of bilirubin (UGT1A1) is found in the ER. Bilirubin translocates to the ER, probably by simple diffusion, to be glucuronylated (Schröter 1972). To date, no transporter has been identified for this process (Fujiwara & Itoh 2014).
Literature References
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Input
Output
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as an event of
Reviewed
Sassa, S  (2007-01-24)
Created
Jassal, B  (2006-11-20)
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