BIL translocates from the cytosol to the ER lumen

Stable Identifier
R-HSA-189381
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The enzyme which catalyzes the conjugation of bilirubin (UGT1A1) is found in the ER. Bilirubin translocates to the ER, probably by simple diffusion, to be glucuronylated (Schröter 1972). To date, no transporter has been identified for this process (Fujiwara & Itoh 2014).
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