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LCT [plasma membrane]
Stable Identifier
R-HSA-189091
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
lactase-phlorizin hydrolase monomer
Locations in the PathwayBrowser
Expand all
Digestion and absorption (Homo sapiens)
Digestion (Homo sapiens)
Digestion of dietary carbohydrate (Homo sapiens)
lactose + H2O => D-glucose + D-galactose (Homo sapiens)
LCT dimer [plasma membrane] (Homo sapiens)
LCT [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
8951031
Proteolytic processing of human lactase-phlorizin hydrolase is a two-step event: identification of the cleavage sites
Jacob, R
,
Wuthrich, M
,
Radebach, I
,
Sterchi, EE
,
Hahn, D
,
Grunberg, J
,
Naim, HY
Arch Biochem Biophys
1996
External Reference Information
External Reference
UniProt:P09848 LCT
Gene Names
LCT, LPH
Chain
signal peptide:1-19, propeptide:20-868, chain:869-1927
Reference Genes
BioGPS Gene:3938 LCT
COSMIC (genes):LCT LCT
CTD Gene:3938 LCT
dbSNP Gene:3938 LCT
ENSEMBL:ENSG00000115850 LCT
HGNC:6530 LCT
KEGG:hsa:3938 LCT
Monarch:3938 LCT
NCBI Gene:3938 LCT
OMIM:603202 LCT
UCSC:P09848 LCT
Reference Transcript
RefSeq:NM_002299.3 LCT
Other Identifiers
11737029_at
16903067
206945_PM_at
206945_at
2577857
2577858
2577859
2577861
2577862
2577864
2577865
2577867
2577869
2577870
2577872
2577873
2577874
2577875
2577876
2577877
2577878
2577880
2577881
2577882
2577884
2577886
2577887
2577889
2577891
2577892
2577893
2577894
2577895
32917_at
3938
8055406
A_23_P79217
GE81142
GO:0000016
GO:0003824
GO:0004336
GO:0004348
GO:0004553
GO:0005886
GO:0005975
GO:0005990
GO:0006629
GO:0008422
GO:0016324
GO:0016787
GO:0016798
GO:0017042
GO:0042803
GO:0046477
GO:0080079
GO:0098591
GO:0140749
GO:1901135
GO:1901733
GO:2000892
HMNXSV003022371
ILMN_1749026
ILMN_2046073
PH_hs_0000302
TC02002374.hg
X07994_at
g4504966_3p_at
Participates
as a component of
LCT dimer [plasma membrane] (Homo sapiens)
Other forms of this molecule
LCT R1587H [plasma membrane]
LCT G1363S [plasma membrane]
Inferred To
Dmel\CG9701 [plasma membrane]
(Drosophila melanogaster)
Lct [plasma membrane]
(Mus musculus)
Lct [plasma membrane]
(Rattus norvegicus)
LOC100625897 [plasma membrane]
(Sus scrofa)
Homologues of LCT [plasma membrane]
(Sus scrofa)
Ghost homologue of LCT [plasma membrane]
(Xenopus tropicalis)
LCT [plasma membrane]
(Bos taurus)
LCT [plasma membrane]
(Canis familiaris)
LCT [plasma membrane]
(Gallus gallus)
LCT [plasma membrane]
(Sus scrofa)
klo-1 [plasma membrane]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENST00000264162
,
ENSP00000264162
,
ENSG00000115850
OpenTargets
ENSG00000115850
ZINC - Substances
LPH_HUMAN
ZINC target
P09848
PRO
P09848
GlyGen
P09848
IntEnz
3.2.1.108
,
3.2.1.62
GeneCards
LCT
HPA
ENSG00000115850-LCT
Pharos - Targets
P09848
Orphanet
LCT
ZINC - Predictions - Purchasable
LPH_HUMAN
HMDB Protein
HMDBP00365
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