Flagellin binds to TLR5

Stable Identifier
R-HSA-188025
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Escherichia coli
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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Flagellin binds to TLR5
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Fragments of extracelllar flagellin bind the TLR5 homodimer.
Literature References
PubMed ID Title Journal Year
15241424 Inferences, questions and possibilities in Toll-like receptor signalling

Beutler, B

Nature 2004
12807870 Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells

Ding, S, Ryan, K, Smith MF, Jr, Li, G, Fitzmaurice, AM, Crowe, S, Mitchell, A, Goldberg, JB

J Biol Chem 2003
11323673 The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Smith, KD, Underhill, DM, Hawn, TR, Goodlett, DR, Ozinsky, A, Aderem, A, Akira, S, Eng, JK, Yi, EC, Hayashi, F

Nature 2001
16439799 AsialoGM1 and TLR5 cooperate in flagellin-induced nucleotide signaling to activate Erk1/2

Basbaum, C, Gallup, M, McNamara, N, McKemy, D, Sucher, A, Maltseva, I

Am J Respir Cell Mol Biol 2006
Participants
Input
Output
Participates
as an event of
Reviewed
Gillespie, ME  (2011-02-10)
Gale M, Jr  (2006-10-31)
Created
de Bono, B  (2006-09-30)
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