Reactome | ZFYVE20 [endosome membrane]

ZFYVE20 [endosome membrane]

Stable Identifier

R-HSA-188000

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

Rabenosyn-5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H1K0 RBSN

Gene Names

RBSN, ZFYVE20

Chain

initiator methionine:, chain:2-784

Reference Genes

BioGPS Gene:64145 RBSN

COSMIC (genes):RBSN RBSN

CTD Gene:64145 RBSN

dbSNP Gene:64145 RBSN

ENSEMBL:ENSG00000131381 RBSN

HGNC:20759 RBSN

KEGG:hsa:64145 RBSN

Monarch:64145 RBSN

NCBI Gene:64145 RBSN

OMIM:609511 RBSN

UCSC:Q9H1K0 RBSN

Reference Transcript

Other Identifiers

11718387_s_at

11747971_s_at

11753186_a_at

1569714_PM_at

1569714_at

16951111

226581_PM_at

226581_at

231765_PM_at

231765_at

2664124

2664125

2664126

2664127

2664128

2664129

2664130

2664131

2664132

2664133

2664134

2664135

2664136

2664137

2664138

2664139

2664140

2664141

2664142

2664143

2664145

2664146

2664147

2664148

2664149

2664150

2664153

2664155

2664160

54804_at

64145

67849_at

74007_at

80412_at

8085537

82654_at

A_23_P315872

A_24_P85181

GE82673

GO:0005515

GO:0005768

GO:0005829

GO:0005886

GO:0008270

GO:0010008

GO:0015031

GO:0016192

GO:0016197

GO:0031267

GO:0031410

GO:0031901

GO:0034498

GO:0043226

GO:0043231

GO:0046872

GO:0070062

GO:0090160

GO:1903358

HMNXSV003007228

HMNXSV003041425

HMNXSV003054379

Hs.167279.0.S2_3p_at

Hs.173002.0.A1_3p_at

Hs2.335336.1.S1_3p_at

ILMN_1799890

PH_hs_0027932

TC03001203.hg

Participates

as a component of

as an input of

This entity regulates

Positively

Rab5-mediated recruitment of class III PI3K to TLR9 (Homo sapiens)

Inferred To

rabs-5 [endosome membrane] (Caenorhabditis elegans)

Rbsn [endosome membrane] (Rattus norvegicus)

rbsn [endosome membrane] (Xenopus tropicalis)

RBSN [endosome membrane] (Canis familiaris)

RBSN [endosome membrane] (Sus scrofa)

Rbsn-5 [endosome membrane] (Drosophila melanogaster)

ZFYVE20 [endosome membrane] (Bos taurus)

ZFYVE20 [endosome membrane] (Gallus gallus)

ZFYVE20 [endosome membrane] (Mus musculus)

ZFYVE20 [endosome membrane] (Saccharomyces cerevisiae)

ZFYVE20 [endosome membrane] (Schizosaccharomyces pombe)

Cross References

ENSEMBL

ENST00000253699, ENSP00000253699, ENSG00000131381, ENSP00000422551, ENST00000476527

OpenTargets

ENSG00000131381

GeneCards

RBSN

HPA

ENSG00000131381-RBSN

PRO

Q9H1K0

Pharos - Targets

Q9H1K0

GlyGen

Q9H1K0

Orphanet

RBSN

HMDB Protein

HMDBP08532

PDB

1Z0K, 1YZM, 1Z0J

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NRW7 VPS45	2	VPS45 [Golgi membrane] (R-HSA-6811025) VPS45 [endosome membrane] (R-HSA-1011607)	0.8	7
UniProt:Q9H4M9 EHD1	1	EHD1 [endosome membrane] (R-HSA-1011616)	0.734	6
UniProt:Q9NZN3 EHD3	1	EHD3 [endosome membrane] (R-HSA-1011601)	0.659	3
UniProt:P20338 RAB4A	5	GGC-RAB4A [cytoplasmic vesicle membrane] (R-HSA-1458526) GGC-RAB4A [cytosol] (R-HSA-8874045) RAB4A [cytosol] (R-HSA-8873709) RAB4A [early endosome membrane] (R-HSA-8871356) GGC-RAB4A [recycling endosome membrane] (R-HSA-8875666)	0.659	4
UniProt:Q9H223 EHD4			0.527	3

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