Inactivation of Cyclin A:Cdk2 complexes by p27/p21

Stable Identifier
R-HSA-187934
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

During G1, the activity of cyclin-dependent kinases (CDKs) is controlled by the CDK inhibitors (CKIs) CDKN1A (p21) and CDKN1B (p27), thereby preventing premature entry into S phase (Guardavaccaro and Pagano, 2006).

Participants
Participant Of
Orthologous Events