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CUL1:SKP1:SKP2 [nucleoplasm]
Stable Identifier
R-HSA-187541
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SCF(Skp2) complex
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1 Phase (Homo sapiens)
Cyclin D associated events in G1 (Homo sapiens)
Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
p-T401,S672,1035-RBL2:SCF(Skp2):Cks1 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Ubiquitination of p130 (RBL2) by SCF (Skp2) (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
p-T401,S672,1035-RBL2:SCF(Skp2):Cks1 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
G1/S Transition (Homo sapiens)
Cyclin E associated events during G1/S transition (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Association of Cks1 with SCF(Skp2) complex (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Ubiquitination of phospho-p27/p21 (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Cyclin A:Cdk2-associated events at S phase entry (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Association of Cks1 with SCF(Skp2) complex (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Ubiquitination of phospho-p27/p21 (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
Participants
components
CUL1 [nucleoplasm]
(Homo sapiens)
SKP1 [nucleoplasm]
(Homo sapiens)
SKP2 [nucleoplasm]
(Homo sapiens)
Participates
as an input of
Association of Cks1 with SCF(Skp2) complex (Homo sapiens)
as a component of
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Inferred To
CUL1:SKP1:SKP2 [nucleoplasm]
(Bos taurus)
CUL1:SKP1:SKP2 [nucleoplasm]
(Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm]
(Canis familiaris)
CUL1:SKP1:SKP2 [nucleoplasm]
(Danio rerio)
CUL1:SKP1:SKP2 [nucleoplasm]
(Dictyostelium discoideum)
CUL1:SKP1:SKP2 [nucleoplasm]
(Drosophila melanogaster)
CUL1:SKP1:SKP2 [nucleoplasm]
(Gallus gallus)
CUL1:SKP1:SKP2 [nucleoplasm]
(Mus musculus)
CUL1:SKP1:SKP2 [nucleoplasm]
(Rattus norvegicus)
CUL1:SKP1:SKP2 [nucleoplasm]
(Sus scrofa)
CUL1:SKP1:SKP2 [nucleoplasm]
(Xenopus tropicalis)
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