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ARP2/3 complex (ATP bound) [cytosol]
Stable Identifier
R-HSA-1861670
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPHB-mediated forward signaling (Homo sapiens)
N-WASP binds ARP2/3 and G-actin (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Role of myosins in phagosome formation (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate WASPs and WAVEs (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Participants
components
ACTR2:ATP [cytosol]
(Homo sapiens)
ACTR3:ATP [cytosol]
(Homo sapiens)
ARPC1A [cytosol]
(Homo sapiens)
ARPC1B [cytosol]
(Homo sapiens)
ARPC2 [cytosol]
(Homo sapiens)
ARPC3 [cytosol]
(Homo sapiens)
ARPC4 [cytosol]
(Homo sapiens)
ARPC5 [cytosol]
(Homo sapiens)
Participates
as a component of
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
as an input of
N-WASP binds ARP2/3 and G-actin (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
Inferred To
ARP2/3 complex (ATP bound) [cytosol]
(Bos taurus)
ARP2/3 complex (ATP bound) [cytosol]
(Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol]
(Canis familiaris)
ARP2/3 complex (ATP bound) [cytosol]
(Danio rerio)
ARP2/3 complex (ATP bound) [cytosol]
(Dictyostelium discoideum)
ARP2/3 complex (ATP bound) [cytosol]
(Drosophila melanogaster)
ARP2/3 complex (ATP bound) [cytosol]
(Gallus gallus)
ARP2/3 complex (ATP bound) [cytosol]
(Mus musculus)
ARP2/3 complex (ATP bound) [cytosol]
(Rattus norvegicus)
ARP2/3 complex (ATP bound) [cytosol]
(Saccharomyces cerevisiae)
ARP2/3 complex (ATP bound) [cytosol]
(Schizosaccharomyces pombe)
ARP2/3 complex (ATP bound) [cytosol]
(Sus scrofa)
ARP2/3 complex (ATP bound) [cytosol]
(Xenopus tropicalis)
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