Synthesis of IP3 and IP4 in the cytosol

Stable Identifier
R-HSA-1855204
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Synthesis of IP3 and IP4 in the cytosol
Click the image above or here to open this pathway in the Pathway Browser

An array of inositol trisphosphate (IP3) and tetrakisphosphate (IP4) molecules are synthesised by the action of various kinases and phosphatases in the cytosol (Irvine & Schell 2001, Bunney & Katan 2010).

Literature References
PubMed ID Title Journal Year
11331907 Back in the water: the return of the inositol phosphates

Schell, MJ, Irvine, RF

Nat Rev Mol Cell Biol 2001
20414202 Phosphoinositide signalling in cancer: beyond PI3K and PTEN

Bunney, TD, Katan, M

Nat Rev Cancer 2010
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
inositol phosphate metabolic process (0043647)
Orthologous Events
Synthesis of IP3 and IP4 in the cytosol (Bos taurus)
Synthesis of IP3 and IP4 in the cytosol (Caenorhabditis elegans)
Synthesis of IP3 and IP4 in the cytosol (Canis familiaris)
Synthesis of IP3 and IP4 in the cytosol (Danio rerio)
Synthesis of IP3 and IP4 in the cytosol (Dictyostelium discoideum)
Synthesis of IP3 and IP4 in the cytosol (Drosophila melanogaster)
Synthesis of IP3 and IP4 in the cytosol (Gallus gallus)
Synthesis of IP3 and IP4 in the cytosol (Mus musculus)
Synthesis of IP3 and IP4 in the cytosol (Plasmodium falciparum)
Synthesis of IP3 and IP4 in the cytosol (Rattus norvegicus)
Synthesis of IP3 and IP4 in the cytosol (Saccharomyces cerevisiae)
Synthesis of IP3 and IP4 in the cytosol (Schizosaccharomyces pombe)
Synthesis of IP3 and IP4 in the cytosol (Sus scrofa)
Synthesis of IP3 and IP4 in the cytosol (Xenopus tropicalis)
Authored
Williams, MG  (2011-10-28)
Created
Williams, MG  (2011-10-28)
Cite Us!