Reactome | I(1,4,5,6)P4 transports from the ER lumen to the nucleus

I(1,4,5,6)P4 transports from the ER lumen to the nucleus

Stable Identifier

R-HSA-1855189

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen, nucleoplasm

ReviewStatus

5/5

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I(1,4,5,6)P4 transports from the ER lumen to the nucleus

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Inositol 1,4,5,6-tetrakisphosphate (I(1,4,5,6)P4) translocates from the endoplasmic reticulum (ER) lumen to the nucleus (Caffrey et al. 1999, Chi et al. 1999, Nalaskowski et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
10087200	Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19 Chi, H, Tiller, GE, Dasouki, MJ, Romano, PR, Wang, J, O'keefe, RJ, Puzas, JE, Rosier, RN, Reynolds, PR	Genomics	1999
9923613	The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification Caffrey, JJ, Hidaka, K, Matsuda, M, Hirata, M, Shears, SB	FEBS Lett	1999
12027805	The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization Nalaskowski, MM, Deschermeier, C, Fanick, W, Mayr, GW	Biochem J	2002

Participants

Input

I(1,4,5,6)P4 [endoplasmic reticulum lumen]

Output

I(1,4,5,6)P4 [nucleoplasm]

Participates

as an event of

IPs transport between ER lumen and nucleus (Homo sapiens)

Event Information

Go Biological Process

nuclear transport (0051169)

Authored

Williams, MG (2011-10-28)

Reviewed

Wundenberg, T (2012-11-07)

Created

Williams, MG (2011-10-28)

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