I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol

Stable Identifier
R-HSA-1855172
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The broad-specificity enzyme inositol-tetrakisphosphate 1-kinase (ITPK1) phosphorylates inositol 1,3,4-trisphosphate (I(1,3,4)P3) to inositol 1,3,4,5-tetrakisphosphate (I(1,3,4,5)P4) (Wilson & Majerus 1996).
Literature References
PubMed ID Title Journal Year
8662638 Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning and expression of the recombinant enzyme

Majerus, PW, Wilson, MP

J Biol Chem 1996
Participants
Participates
Catalyst Activity

inositol-1,3,4-trisphosphate 5-kinase activity of ITPK1:Mg2+ [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Created
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