Reactome | I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol

I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol

Stable Identifier

R-HSA-1855159

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

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I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol

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Inositol-tetrakisphosphate 1-kinase (ITPK1) dephosphorylates inositol 1,3,4,6-tetrakisphosphate (I(1,3,4,6)P4) to inositol 3,4,6-trisphosphate (I(3,4,6)P3) (Ho et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
11909533	Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase Ho, MW, Yang, X, Carew, MA, Zhang, T, Hua, L, Kwon, YU, Chung, SK, Adelt, S, Vogel, G, Riley, AM, Potter, BV, Shears, SB	Curr Biol	2002