Reactome | VPS28 [endosome membrane]

VPS28 [endosome membrane]

Stable Identifier

R-HSA-184342

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UK41 VPS28

Gene Names

VPS28

Chain

chain:1-221

Reference Genes

BioGPS Gene:51160 VPS28

COSMIC (genes):VPS28 VPS28

CTD Gene:51160 VPS28

dbSNP Gene:51160 VPS28

ENSEMBL:ENSG00000160948 VPS28

HGNC:18178 VPS28

KEGG:hsa:51160 VPS28

Monarch:51160 VPS28

NCBI Gene:51160 VPS28

OMIM:611952 VPS28

UCSC:Q9UK41 VPS28

Reference Transcript

Participates

as a component of

ESCRT-I [endosome membrane] (Homo sapiens)

Inferred To

Ghost homologue of VPS28 [endosome membrane] (Gallus gallus)

vps-28 [endosome membrane] (Caenorhabditis elegans)

Vps28 [endosome membrane] (Drosophila melanogaster)

Vps28 [endosome membrane] (Mus musculus)

Vps28 [endosome membrane] (Rattus norvegicus)

vps28 [endosome membrane] (Danio rerio)

vps28 [endosome membrane] (Dictyostelium discoideum)

VPS28 [endosome membrane] (Bos taurus)

VPS28 [endosome membrane] (Canis familiaris)

VPS28 [endosome membrane] (Saccharomyces cerevisiae)

VPS28 [endosome membrane] (Sus scrofa)

Cross References

RefSeq

NP_057292.1, NP_898880.1

ENSEMBL

ENST00000377348, ENST00000292510, ENST00000643186, ENSP00000434556, ENSP00000292510, ENST00000642202, ENSP00000495408, ENST00000646588, ENST00000529182, ENSP00000496519, ENSG00000160948, ENST00000526054, ENST00000642867, ENSG00000285339, ENSP00000496693, ENSP00000366565, ENSP00000434064, ENSP00000494521

OpenTargets

ENSG00000160948

GeneCards

VPS28

HPA

ENSG00000160948-VPS28

PRO

Q9UK41

Pharos - Targets

Q9UK41

GlyGen

Q9UK41

PDB

6VME

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	16
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	6
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.527	2

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