Reactome | VPS37A [endosome membrane]

VPS37A [endosome membrane]

Stable Identifier

R-HSA-184333

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8NEZ2 VPS37A

Gene Names

VPS37A, HCRP1

Chain

chain:1-397

Reference Genes

BioGPS Gene:137492 VPS37A

COSMIC (genes):VPS37A VPS37A

CTD Gene:137492 VPS37A

dbSNP Gene:137492 VPS37A

ENSEMBL:ENSG00000155975 VPS37A

ENSEMBL_homo_sapiens_GENE:ENSG00000155975.10 VPS37A

HGNC:24928 VPS37A

KEGG Gene (Homo sapiens):137492 VPS37A

Monarch:137492 VPS37A

NCBI Gene:137492 VPS37A

OMIM:609927 VPS37A

UCSC:Q8NEZ2 VPS37A

Reference Transcript

Other Identifiers

11725342_a_at

11725343_a_at

11725344_a_at

137492

17066036

225378_PM_at

225378_at

228024_PM_at

228024_at

3087559

3087560

3087561

3087562

3087567

3087568

3087570

3087571

3087572

3087573

3087574

3087576

3087577

3087578

3087579

3087582

3087585

3087589

3087590

3087591

3087592

3087593

3087594

3087595

3087596

3087597

3087598

61863_at

63312_r_at

65242_at

74777_at

8144774

84345_at

84348_g_at

A_14_P106165

A_23_P366328

A_24_P941649

A_33_P3303850

GE53583

GO:0000813

GO:0005515

GO:0005634

GO:0005654

GO:0005768

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0006612

GO:0006623

GO:0006886

GO:0006914

GO:0009056

GO:0010008

GO:0015031

GO:0016020

GO:0016192

GO:0016236

GO:0030163

GO:0031410

GO:0031902

GO:0036258

GO:0039702

GO:0043162

GO:0043226

GO:0043231

GO:0043328

GO:0061024

GO:0090148

HMNXSV003021241

HMNXSV003048901

Hs.101617.0.A1_3p_at

Hs.290855.0.S1_3p_at

ILMN_1711139

ILMN_2161832

PH_hs_0028158

TC08000126.hg

Participates

as a member of

VPS37 [endosome membrane] (Homo sapiens)

Inferred To

zgc:77637 [endosome membrane] (Danio rerio)

VPS37A [endosome membrane] (Bos taurus)

VPS37A [endosome membrane] (Canis familiaris)

VPS37A [endosome membrane] (Gallus gallus)

VPS37A [endosome membrane] (Rattus norvegicus)

VPS37A [endosome membrane] (Sus scrofa)

SRN2 [endosome membrane] (Saccharomyces cerevisiae)

vps37 [endosome membrane] (Dictyostelium discoideum)

Vps37a [endosome membrane] (Mus musculus)

Vsp37A [endosome membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_689628.2, XP_016868511.1, XP_016868510.1, NP_001138624.1, XP_016868515.1

OpenTargets

ENSG00000155975

GeneCards

Q8NEZ2

HPA

ENSG00000155975-VPS37A

Ensembl

ENSP00000318629, ENSP00000412824, ENST00000324849, ENSP00000429680, ENST00000425020, ENST00000521829, ENSG00000155975

PRO

Q8NEZ2

Pharos - Targets

Q8NEZ2

Orphanet

21757

PDB

8E22

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:P54252 ATXN3	2	ATXN3 [nucleoplasm] (R-HSA-6783285) ATXN3 [cytosol] (R-HSA-5625607)	0.556	3
UniProt:P35240 NF2	1	NF2 [plasma membrane] (R-HSA-5669168)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6