Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
VPS37D [endosome membrane]
Stable Identifier
R-HSA-184289
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Late endosomal microautophagy (Homo sapiens)
Substrate translocates into late endosomal lumen (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Late Events (Homo sapiens)
HCMV Final Envelopment (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
HCMV Formation of Final Envelopment Complex (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)
Membrane binding and targetting of GAG proteins (Homo sapiens)
Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
Transport of GAG to the Plasma Membrane (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
Cargo Recognition And Sorting (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
Cargo Sequestration (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37D [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86XT2 VPS37D
Gene Names
VPS37D, WBSCR24
Chain
chain:1-251
Reference Genes
BioGPS Gene:155382 VPS37D
COSMIC (genes):VPS37D VPS37D
CTD Gene:155382 VPS37D
dbSNP Gene:155382 VPS37D
ENSEMBL:ENSG00000176428 VPS37D
HGNC:18287 VPS37D
KEGG:hsa:155382 VPS37D
Monarch:155382 VPS37D
NCBI Gene:155382 VPS37D
OMIM:610039 VPS37D
UCSC:Q86XT2 VPS37D
Reference Transcript
RefSeq:NM_001077621.1 VPS37D
Other Identifiers
11726825_at
11726826_s_at
155382
17046942
235569_PM_at
235569_at
3007876
3007877
3007878
3007879
3007881
3007883
3007884
8133339
81931_at
A_33_P3293573
GO:0000813
GO:0005515
GO:0005768
GO:0006612
GO:0006623
GO:0006886
GO:0006914
GO:0009056
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0016236
GO:0031410
GO:0031902
GO:0036258
GO:0039702
GO:0043162
GO:0043226
GO:0043328
GO:0061024
GO:0070062
GO:0090148
HMNXSV003038527
Hs.126451.0.A1_3p_at
ILMN_1692865
PH_hs_0031637
TC07000442.hg
Participates
as a member of
VPS37 [endosome membrane] (Homo sapiens)
Inferred To
Vps37d [endosome membrane]
(Mus musculus)
Vps37d [endosome membrane]
(Rattus norvegicus)
SRN2 [endosome membrane]
(Saccharomyces cerevisiae)
Vps37B [endosome membrane]
(Drosophila melanogaster)
vps37 [endosome membrane]
(Dictyostelium discoideum)
vps-37 [endosome membrane]
(Caenorhabditis elegans)
VPS37D [endosome membrane]
(Bos taurus)
VPS37D [endosome membrane]
(Canis familiaris)
VPS37D [endosome membrane]
(Gallus gallus)
VPS37D [endosome membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001071089.1
ENSEMBL
ENST00000324941
,
ENSP00000320416
OpenTargets
ENSG00000176428
HPA
ENSG00000176428-VPS37D
PRO
Q86XT2
Pharos - Targets
Q86XT2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text