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cytosolic FGFR1 fusion mutant dimers [cytosol]
Stable Identifier
R-HSA-1839026
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)
Dimerization of cytosolic FGFR1 fusion proteins (Homo sapiens)
cytosolic FGFR1 fusion mutant dimers [cytosol] (Homo sapiens)
Phosphorylation of cytosolic FGFR1 fusion dimers (Homo sapiens)
cytosolic FGFR1 fusion mutant dimers [cytosol] (Homo sapiens)
Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation (Homo sapiens)
FGFR1 fusion mutant dimers:TKIs [cytosol] (Homo sapiens)
cytosolic FGFR1 fusion mutant dimers [cytosol] (Homo sapiens)
cytosolic FGFR1 fusion mutant dimers [cytosol] (Homo sapiens)
Participants
members
ZMYM2-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
FGFR1OP-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
CNTRL-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
BCR-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
FGFR1OP2-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
TRIM24-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
CUX1-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
candidates
CPSF6-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
LRRFIP1-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
MYO18A-FGFR1 fusion mutant dimer [cytosol]
(Homo sapiens)
Participates
as a component of
FGFR1 fusion mutant dimers:TKIs [cytosol] (Homo sapiens)
as an input of
Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation (Homo sapiens)
Phosphorylation of cytosolic FGFR1 fusion dimers (Homo sapiens)
as an output of
Dimerization of cytosolic FGFR1 fusion proteins (Homo sapiens)
Disease
Name
Identifier
Synonyms
subacute leukemia
DOID:3264
myelodysplastic myeloproliferative cancer
DOID:4972
Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
acute lymphocytic leukemia
DOID:9952
chronic myeloid leukemia
DOID:8552
CML, chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality), chronic myeloid leukemia, disease (disorder), chronic myeloid leukemia without mention of remission, CML - chronic Myelogenous Leukemia, chronic myeloid leukemia in remission (disorder), Myeloid Leukemia, chronic, CML in Remission, chronic myeloid leukemia in remission, chronic myeloid leukaemia, chronic myeloid leukemia NOS (disorder)
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