Factor B binds to surface-associated C3b

Stable Identifier
R-HSA-183126
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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Factor B binds to surface-associated C3b
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C3b on a surface binds Factor B from solution to form a complex (Schreiber et al. 1978; Muller-Eberhard 1988).
Literature References
PubMed ID Title Journal Year
279011 Initiation of the alternative pathway of complement: recognition of activators by bound C3b and assembly of the entire pathway from six isolated proteins

Schreiber, RD, Pangburn, MK, Muller-Eberhard, HJ, Lesavre, PH

Proc Natl Acad Sci U S A 1978
3052276 Molecular organization and function of the complement system

Muller-Eberhard, HJ

Annu Rev Biochem 1988
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Authored
de Bono, B  (2006-07-21)
Reviewed
D'Eustachio, P  (2006-08-29)
Created
de Bono, B  (2006-07-21)
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