p16INK4A [cytosol]

Stable Identifier
R-HSA-182578
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Cyclin-dependent kinase inhibitor 2A, MTS1, CDK4I
Icon
p16INK4A [cytosol] icon
p16INK4A [cytosol] icon
Locations in the PathwayBrowser for interactor UniProt:O75398 DEAF1
Expand all
External Reference Information
External Reference
UniProt:P42771 CDKN2A
Gene Names
CDKN2A, CDKN2, MLM, MTS1
Chain
chain:1-156
Reference Genes
BioGPS Gene:1029 CDKN2A
COSMIC (genes):CDKN2A CDKN2A
CTD Gene:1029 CDKN2A
dbSNP Gene:1029 CDKN2A
ENSEMBL:ENSG00000147889 CDKN2A
ENSEMBL_homo_sapiens_GENE:ENSG00000147889.18 CDKN2A
KEGG Gene (Homo sapiens):1029 CDKN2A
Monarch:1029 CDKN2A
NCBI Gene:1029 CDKN2A
OMIM:600160 CDKN2A
UCSC:P42771 CDKN2A
Reference Transcript
Other Identifiers
1029
11718293_a_at
1713_s_at
207039_PM_at
207039_at
209644_PM_x_at
209644_x_at
211156_PM_at
211156_at
3201444
3201445
3201446
3201447
3201448
3201450
3201451
3201457
3201458
3201459
3201460
3201461
3201464
3201465
3201466
3201467
3201477
3201478
3201483
3201485
73132_r_at
8160441
A_23_P43484
A_23_P43490
A_33_P3411628
GE59038
GO:0000278
GO:0001953
GO:0003723
GO:0004861
GO:0005515
GO:0005634
GO:0005694
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0007049
GO:0007155
GO:0007265
GO:0008285
GO:0012501
GO:0019901
GO:0023052
GO:0030308
GO:0032088
GO:0034393
GO:0035985
GO:0036211
GO:0042326
GO:0043226
GO:0045736
GO:0045892
GO:0051059
GO:0051726
GO:0090398
GO:0090399
GO:0098772
GO:2000045
GO:2000111
HMNXSV003019577
ILMN_1717714
ILMN_1757255
PH_hs_0019731
U26727_at
g1353569_3p_a_at
g1353569_3p_x_at
g4206166_3p_a_at
g4502748_3p_at
Participates
as an output of
as a member of
Other forms of this molecule
p16INK4A D84G [cytosol]
p16INK4A E88* [cytosol]
p16INK4A R87P [cytosol]
p16INK4A V126D [cytosol]
p16INK4A W110* [cytosol]
p16INK4A D84H [cytosol]
p16INK4A R80* [cytosol]
p16INK4A P114L [cytosol]
p16INK4A R58* [cytosol]
p16INK4A D84N [cytosol]
p16INK4A M53I [cytosol]
p16INK4A D84Y [cytosol]
p16INK4A G101W [cytosol]
p16INK4A P81L [cytosol]
p16INK4A A20P [cytosol]
p16INK4A D84V [cytosol]
p16INK4A P81T [cytosol]
p16INK4A P81H [cytosol]
p16INK4A D84A [cytosol]
p16INK4A P81R [cytosol]
p16INK4A E10* [cytosol]
p16INK4A S12* [cytosol]
p16INK4A P114T [cytosol]
p16INK4A P114S [cytosol]
p16INK4A G23fs*3 [cytosol]
p16INK4A E61* [cytosol]
p16INK4A A20T [cytosol]
p16INK4A A36fs*17 [cytosol]
p16INK4A E69* [cytosol]
p16INK4A W15fs*1 [cytosol]
p16INK4A T18fs*15 [cytosol]
p16INK4A E26* [cytosol]
p16INK4A E33* [cytosol]
p16INK4A Q50* [cytosol]
p16INK4A E120* [cytosol]
p16INK4A S7fs*8 [cytosol]
p16INK4A W15* [cytosol]
p16INK4A P75* [cytosol]
p16INK4A C72* [cytosol]
p16INK4A E119* [cytosol]
p16INK4A A20E [cytosol]
p16INK4A N39fs*14 [cytosol]
p16INK4A P114R [cytosol]
p16INK4A P114H [cytosol]
p16INK4A E27* [cytosol]
p16INK4A P81S [cytosol]
p16INK4A G101V [cytosol]
p16INK4A Y44* [cytosol]
p16INK4A V126I [cytosol]
p16INK4A L16fs*9 [cytosol]
p16INK4A V126A [cytosol]
p16INK4A T18fs*8 [cytosol]
p16INK4A V126F [cytosol]
p16INK4A L37fs*16 [cytosol]
p16INK4A G35V [cytosol]
p16INK4A G23D [cytosol]
p16INK4A R24P [cytosol]
p16INK4A R80P [cytosol]
p16INK4A G35A [cytosol]
p16INK4A E88K [cytosol]
p16INK4A T77P [cytosol]
p16INK4A L97R [cytosol]
p16INK4A T18_A19dup [cytosol]
p16INK4A G67_N71del [cytosol]
p16INK4A A60R [cytosol]
p16INK4A D74Y [cytosol]
p16INK4A A60V [cytosol]
p16INK4A R112dup [cytosol]
p16INK4A R99P [cytosol]
p16INK4A A60S [cytosol]
p16INK4A L97P [cytosol]
p16INK4A G23S [cytosol]
p16INK4A A60E [cytosol]
p16INK4A G23V [cytosol]
p16INK4A G35R [cytosol]
p16INK4A T77S [cytosol]
p16INK4A G35W [cytosol]
p16INK4A G35E [cytosol]
Inferred To
Cdkn2b [cytosol] (Mus musculus)
Cdkn2b [cytosol] (Rattus norvegicus)
CDKN2B [cytosol] (Bos taurus)
CDKN2B [cytosol] (Canis familiaris)
CDKN2B [cytosol] (Gallus gallus)
CDKN2B [cytosol] (Sus scrofa)
cdkn2b [cytosol] (Xenopus tropicalis)
CDKN2A [cytosol] (Sus scrofa)
Homologues of p16INK4A [cytosol] (Sus scrofa)
Homologues of p16INK4A [cytosol] (Xenopus tropicalis)
LOC100488442 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (12)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P11802 CDK4  3 0.96 19
 UniProt:Q00534 CDK6  3 0.949 19
 UniProt:P12004 PCNA  5 0.61 8
 UniProt:P02730 SLC4A1  8 0.602 5
 UniProt:O75496 GMNN  2 0.592 2
 UniProt:Q6UXH1 CREL2      0.508 2
 UniProt:Q8NHU6 TDRD7      0.508 2
 UniProt:O75398 DEAF1      0.508 2
 UniProt:Q00839 HNRNPU  1 0.508 2
 UniProt:Q14566 MCM6  1 0.499 4
 UniProt:P24385 CCND1  4 0.491 2
 UniProt:P62826 RAN  2 0.463 2
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