Degradation of CD8

Stable Identifier
R-HSA-182171
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
cytosol
ReviewStatus
5/5
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Degradation of CD8
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Once the CD8alphabeta receptor has been internalized via endocytosis, the vesicles are targeted for lysosomal degradation.

Literature References
PubMed ID Title Journal Year
16103193 Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta

Verhasselt, B, Naessens, E, Coene, E, Stove, C, Van de Walle, I, Plum, J, Stove, V

J Virol 2005
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Gillespie, ME  (2007-07-25)
Reviewed
Skowronski, J  (2007-08-07)
Created
Gillespie, ME  (2006-07-06)
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