Reactome | STX1B [plasma membrane]

STX1B [plasma membrane]

Stable Identifier

R-HSA-181479

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Syntaxin 1B

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Uptake and actions of bacterial toxins (Homo sapiens)
    - Neurotoxicity of clostridium toxins (Homo sapiens)
      - Toxicity of botulinum toxin type C (botC) (Homo sapiens)
        
        botC LC cleaves target cell STX1 (Homo sapiens)
        
        STX1 [plasma membrane] (Homo sapiens)
        
        STX1B [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P61266 STX1B

Gene Names

STX1B, STX1B1, STX1B2

Chain

chain:1-288

Reference Genes

BioGPS Gene:112755 STX1B

COSMIC (genes):STX1B STX1B

CTD Gene:112755 STX1B

dbSNP Gene:112755 STX1B

ENSEMBL:ENSG00000099365 STX1B

HGNC:18539 STX1B

KEGG Gene (Homo sapiens):112755 STX1B

Monarch:112755 STX1B

NCBI Gene:112755 STX1B

OMIM:601485 STX1B

UCSC:P61266 STX1B

Reference Transcript

RefSeq:NM_052874.4 STX1B

Other Identifiers

0005220164

112755

11729945_at

11729946_at

16825911

230691_at

3688107

3688109

3688111

3688113

3688114

3688115

3688116

3688117

3688119

3688121

3688122

3688123

3688124

3688125

3688127

3688129

3688130

3688132

3688133

3688135

3688139

3688140

56284_at

8000963

A_23_P152462

A_33_P3326382

GE56921

GO:0000149

GO:0001956

GO:0003674

GO:0005102

GO:0005484

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005652

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005819

GO:0005829

GO:0005856

GO:0005886

GO:0006810

GO:0006836

GO:0006886

GO:0006887

GO:0006904

GO:0006906

GO:0007165

GO:0007267

GO:0008021

GO:0008150

GO:0010468

GO:0010807

GO:0010977

GO:0012505

GO:0015031

GO:0016020

GO:0016021

GO:0016079

GO:0016081

GO:0016192

GO:0017157

GO:0019899

GO:0019901

GO:0019904

GO:0022607

GO:0030154

GO:0030424

GO:0030674

GO:0031201

GO:0031410

GO:0031594

GO:0031629

GO:0032991

GO:0042734

GO:0043226

GO:0048278

GO:0048787

GO:0048791

GO:0048856

GO:0050877

GO:0060025

GO:0061024

GO:0061669

GO:0065003

GO:0072657

GO:0098793

GO:0098967

GO:1903422

GO:1904050

GO:1905302

GO:2000463

HMNXSV003009807

HMNXSV003013143

HMNXSV003027091

Hs.21782.0.A1_3p_at

ILMN_1660721

ILMN_3189972

ILMN_3234081

PH_hs_0024290

PH_hs_0038944

TC16001047.hg

Participates

as a member of

STX1 [plasma membrane] (Homo sapiens)

Other forms of this molecule

STX1B(1-?) [cytosol]

STX1B(?-288) [plasma membrane]

Inferred To

stx1b [plasma membrane] (Danio rerio)

Stx1b [plasma membrane] (Mus musculus)

Stx1b [plasma membrane] (Rattus norvegicus)

STX1B [plasma membrane] (Canis familiaris)

STX1B [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_443106.1

OpenTargets

ENSG00000099365

HPA

ENSG00000099365-STX1B

GeneCards

P61266

Ensembl

ENST00000565419, ENSP00000215095, ENSP00000455899, ENSG00000099365, ENST00000215095

PRO

P61266

Pharos - Targets

P61266

Orphanet

23093

GlyGen

P61266

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N4V1 MMGT1	1	MMGT1 [Golgi membrane] (R-HSA-5216137)	0.556	3
UniProt:P40222 TXLNA	1	TXLNA [cytosol] (R-HSA-449124)	0.556	3
UniProt:P63027 VAMP2	20	VAMP2 [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-379363) VAMP2 [plasma membrane] (R-HSA-210516) VAMP2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917738) VAMP2 [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-210365) VAMP2 [synaptic vesicle membrane] (R-HSA-181517) VAMP2(59-116) [synaptic vesicle membrane] (R-HSA-5250891) VAMP2(2-58) [cytosol] (R-HSA-194815) VAMP2(2-76) [cytosol] (R-HSA-194802) VAMP2(77-116) [synaptic vesicle membrane] (R-HSA-5228355) VAMP2(60-116) [synaptic vesicle membrane] (R-HSA-5250615) VAMP2(2-59) [cytosol] (R-HSA-194797) VAMP2(82-116) [synaptic vesicle membrane] (R-HSA-5250961) VAMP2(2-81) [cytosol] (R-HSA-5250970) VAMP2 [secretory granule membrane] (R-HSA-376363) VAMP2 [cytosol] (R-HSA-9609882) VAMP2 [endoplasmic reticulum membrane] (R-HSA-9609886) VAMP2 [cytoplasmic vesicle membrane] (R-HSA-1449630) VAMP2 [lysosomal membrane] (R-HSA-432703) VAMP2 [Golgi membrane] (R-HSA-375425) VAMP2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869129)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:Q12846 STX4	4	STX4 [plasma membrane] (R-HSA-181519) STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.556	3
UniProt:O15155 BET1	3	BET1 [Golgi membrane] (R-HSA-6807743) BET1 [transport vesicle] (R-HSA-6808719) BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142)	0.556	3
UniProt:O15554 KCNN4	1	KCNN4 [plasma membrane] (R-HSA-977543)	0.556	3