Rev associates with B23

Stable Identifier
R-HSA-180725
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
cytosol
ReviewStatus
5/5
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Rev associates with B23
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
B23 may function as a shuttle for the import of HIV Rev from the cytoplasm into the nucleus or nucleolus permitting additional rounds of export of viral RNAs.
Literature References
PubMed ID Title Journal Year
2017166 Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element

Wingfield, P, Adachi, Y, Fankhauser, C, Laemmli, UK, Izaurralde, E

Mol Cell Biol 1991
9092824 Nucleolar protein B23 stimulates nuclear import of the HIV-1 Rev protein and NLS-conjugated albumin

Mehrotra, B, Wingfield, PT, Baumann, A, Szebeni, A, Olson, MO, Adam, SA

Biochemistry 1997
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Matthews, L  (2006-06-08)
Reviewed
Kumar, A  (2007-02-01)
Created
Matthews, L  (2006-06-02)
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