Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
p-T75-DARPP32s [cytosol]
Stable Identifier
R-HSA-180026
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
DARPP-32 events (Homo sapiens)
CDK5 phosphorylates DARPP-32 on Thr75 (Homo sapiens)
p-T75-DARPP32s [cytosol] (Homo sapiens)
DARPP-32 is dephosphorylated on Thr75 by PP2A (Homo sapiens)
p-T75-DARPP32s [cytosol] (Homo sapiens)
DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Homo sapiens)
p-T75-DARPP32s [cytosol] (Homo sapiens)
p-T75-DARPP32s:PRKACA [cytosol] (Homo sapiens)
p-T75-DARPP32s [cytosol] (Homo sapiens)
PKA phosphorylates PDE4B (Homo sapiens)
p-T75-DARPP32s [cytosol] (Homo sapiens)
Participants
members
p-T75-PPP1R1B [cytosol]
(Homo sapiens)
p-T75,S102-PPP1R1B [cytosol]
(Homo sapiens)
p-T75,S102,S137-PPP1R1B [cytosol]
(Homo sapiens)
p-T34,T75,S102,S137-PPP1R1B [cytosol]
(Homo sapiens)
p-T34,T75,S102-PPP1R1B [cytosol]
(Homo sapiens)
p-T75,S137-PPP1R1B [cytosol]
(Homo sapiens)
p-T34,T75,S137-PPP1R1B [cytosol]
(Homo sapiens)
p-T34,T75-PPP1R1B [cytosol]
(Homo sapiens)
Participates
as an input of
DARPP-32 is dephosphorylated on Thr75 by PP2A (Homo sapiens)
DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Homo sapiens)
as an output of
CDK5 phosphorylates DARPP-32 on Thr75 (Homo sapiens)
as a component of
p-T75-DARPP32s:PRKACA [cytosol] (Homo sapiens)
This entity regulates
Negatively
PKA phosphorylates PDE4B
(Homo sapiens)
Inferred To
phospho-ppp1r1b [cytosol]
(Xenopus tropicalis)
p-T75-DARPP32s [cytosol]
(Gallus gallus)
phospho-PPP1R1B [cytosol]
(Bos taurus)
phospho-PPP1R1B [cytosol]
(Canis familiaris)
phospho-PPP1R1B [cytosol]
(Sus scrofa)
phospho-Ppp1r1b [cytosol]
(Mus musculus)
phospho-Ppp1r1b [cytosol]
(Rattus norvegicus)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text