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Expression of TPP1
Stable Identifier
R-HSA-1791138
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
,
lysosomal lumen
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Unfolded Protein Response (UPR) (Homo sapiens)
IRE1alpha activates chaperones (Homo sapiens)
XBP1(S) activates chaperone genes (Homo sapiens)
Expression of TPP1 (Homo sapiens)
General
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The TPP1 gene is transcribed to yield mRNA and the mRNA is translated to yield protein.
Literature References
PubMed ID
Title
Journal
Year
16539657
XBP1 induces WFS1 through an endoplasmic reticulum stress response element-like motif in SH-SY5Y cells
Kato, T
,
Ishiwata, M
,
Hayashi, A
,
Kakiuchi, C
J Neurochem
2006
Participants
Input
TPP1 gene [nucleoplasm]
(Homo sapiens)
Output
TPP1 [lysosomal lumen]
(Homo sapiens)
Participates
as an event of
XBP1(S) activates chaperone genes (Homo sapiens)
This event is regulated
Positively by
Regulator
XBP1-2 [nucleoplasm]
(Homo sapiens)
Authored
May, B (2011-10-13)
Reviewed
Gillespie, ME (2008-12-02)
D'Eustachio, P (2008-12-02)
Matthews, L (2008-12-02)
Urano, F (2010-04-30)
Created
May, B (2011-10-21)
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