Reactome | GAB1 phosphorylation by EGFR kinase

GAB1 phosphorylation by EGFR kinase

Stable Identifier

R-HSA-177930

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol, plasma membrane, extracellular region

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EGFR kinase phosphorylates the phosphorylation sites tyrosine 627 and 659 on GAB1

Literature References

PubMed ID	Title	Journal	Year
9890893	Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro Lehr, S, Kotzka, J, Herkner, A, Klein, E, Siethoff, C, Knebel, B, Noelle, V, Bruning, JC, Klein, HW, Meyer, HE, Krone, W, Muller-Wieland, D	Biochemistry	1999
15231819	Ligand regulates epidermal growth factor receptor kinase specificity: activation increases preference for GAB1 and SHC versus autophosphorylation sites Fan, YX, Wong, L, Deb, TB, Johnson, GR	J Biol Chem	2004