GAB1 phosphorylation by EGFR kinase

Stable Identifier
R-HSA-177930
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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EGFR kinase phosphorylates the phosphorylation sites tyrosine 627 and 659 on GAB1

Literature References
PubMed ID Title Journal Year
9890893 Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro

Lehr, S, Kotzka, J, Herkner, A, Klein, E, Siethoff, C, Knebel, B, Noelle, V, Bruning, JC, Klein, HW, Meyer, HE, Krone, W, Muller-Wieland, D

Biochemistry 1999
15231819 Ligand regulates epidermal growth factor receptor kinase specificity: activation increases preference for GAB1 and SHC versus autophosphorylation sites

Fan, YX, Wong, L, Deb, TB, Johnson, GR

J Biol Chem 2004
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]
Physical Entity
Activity
Orthologous Events
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Reviewed
Created