GAB1 phosphorylation by EGFR kinase

Stable Identifier
R-HSA-177930
Type
Reaction
Species
Homo sapiens
Compartment
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EGFR kinase phosphorylates the phosphorylation sites tyrosine 627 and 659 on GAB1

Literature References
PubMed ID Title Journal Year
15231819 Ligand regulates epidermal growth factor receptor kinase specificity: activation increases preference for GAB1 and SHC versus autophosphorylation sites

Deb, TB, Wong, L, Johnson, GR, Fan, YX

J Biol Chem 2004
9890893 Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro

Bruning, JC, Knebel, B, Lehr, S, Siethoff, C, Herkner, A, Muller-Wieland, D, Krone, W, Klein, E, Kotzka, J, Meyer, HE, Klein, HW, Noelle, V

Biochemistry 1999
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]

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