viral dsRNA:TLR3:TRIF:TRAF6 [endosome membrane]

Stable Identifier
Homo sapiens
Related Species
Influenza A virus, Rotavirus, Hepatitis B virus, Hepatitis C Virus, Human herpesvirus 1
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
16115877 Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

Fitzgerald, KA, Cusson-Hermance, N, Khurana, S, Kelliher, MA, Lee, TH

J Biol Chem 2005
20047764 Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway

Matsumoto, M, Hatakeyama, S, Oshiumi, H, Funami, K, Seya, T, Sasai, M, Tatematsu, M

Mol Immunol 2010
14982987 Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta

Li, X, Sen, G, Mak, TW, Jiang, Z

Proc. Natl. Acad. Sci. U.S.A. 2004
16306937 Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

Hsu, LC, Raz, E, Häcker, G, Karin, M, Kamps, MP, Mann, M, Kratchmarova, I, Redecke, V, Blagoev, B, Häcker, H, Wagner, H, Wang, GG

Nature 2006
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