Formation of clathrin-coated vesicle

Stable Identifier
R-HSA-177491
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Both BDNF and NGF treatment recruits clathrin and AP2 (adaptor protein 2) proteins to the plasma membrane. Clathrin is the major protein of the polyhedral coat of vesicles. The AP2 complex mediates both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

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