Association of MCM8 with ORC:origin complex

Stable Identifier
R-HSA-176973
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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Association of MCM8 with ORC:origin complex
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The MCM2-7 complex, an essential component of the pre-replication complex, recruits CDC6 and CDT1 proteins to the origin. MCM8, another member of the MCM family has been found to bind to chromatin during early G1 phase. MCM8 interacts specifically with the ORC2 protein.

Literature References
PubMed ID Title Journal Year
15684404 Involvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatin

Volkening, M, Hoffmann, I

Mol Cell Biol 2005
Participants
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Output
Participant Of
hasEvent
Orthologous Events
Association of MCM8 with ORC:origin complex (Canis familiaris)
Association of MCM8 with ORC:origin complex (Danio rerio)
Association of MCM8 with ORC:origin complex (Dictyostelium discoideum)
Association of MCM8 with ORC:origin complex (Drosophila melanogaster)
Association of MCM8 with ORC:origin complex (Gallus gallus)
Association of MCM8 with ORC:origin complex (Mus musculus)
Association of MCM8 with ORC:origin complex (Rattus norvegicus)
Association of MCM8 with ORC:origin complex (Sus scrofa)
Association of MCM8 with ORC:origin complex (Xenopus tropicalis)
Authored
Tye, BK  (2006-03-17)
Created
Gopinathrao, G  (2006-03-18)