Association of MCM8 with ORC:origin complex

Stable Identifier
R-HSA-176973
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The MCM2-7 complex, an essential component of the pre-replication complex, recruits CDC6 and CDT1 proteins to the origin. MCM8, another member of the MCM family has been found to bind to chromatin during early G1 phase. MCM8 interacts specifically with the ORC2 protein.

Literature References
PubMed ID Title Journal Year
15684404 Involvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatin

Volkening, M, Hoffmann, I

Mol Cell Biol 2005
Participants
Participant Of
Orthologous Events
Authored
Created