p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP

Stable Identifier
R-HSA-176646
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The sulfonation of the xenobiotic p-nitrophenol (4-nitrophenol) can be catalyzed by five well-characterized SULT enzymes, 1A1 (Brix et al. 1998), 1A2 (Brix et al. 1998; Zhu et al. 1996), 1C2 (Sakakibara et al. 1998), and 4A1 (Sakakibara et al. 2002).

Literature References
PubMed ID Title Journal Year
9566739 Structural and functional characterisation of human sulfotransferases

Brix, LA, Nicoll, R, Zhu, X, McManus, ME

Chem Biol Interact 1998
9852044 Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2-acetylaminofluorene

Sakakibara, Y, Yanagisawa, K, Katafuchi, J, Ringer, DP, Takami, Y, Nakayama, T, Suiko, M, Liu, MC

J Biol Chem 1998
12039030 Highly conserved mouse and human brain sulfotransferases: molecular cloning, expression, and functional characterization

Sakakibara, Y, Suiko, M, Pai, TG, Nakayama, T, Takami, Y, Katafuchi, J, Liu, MC

Gene 2002
8697101 cDNA cloning and expression of a new form of human aryl sulfotransferase

Zhu, X, Veronese, ME, Iocco, P, McManus, ME

Int J Biochem Cell Biol 1996
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
aryl sulfotransferase activity of SULT1A1,A2,C2,4A1 [cytosol]
Physical Entity
Activity
Orthologous Events
Reviewed
Created
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