lithocholate + PAPS => lithocholate sulfate + PAP

Stable Identifier
R-HSA-176588
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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lithocholate + PAPS => lithocholate sulfate + PAP
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Sulfonation of lithocholate is catalyzed by SULT2A1 (Radominska et al. 1990).
Literature References
PubMed ID Title Journal Year
2268288 Human liver steroid sulphotransferase sulphates bile acids

Radominska, A, Comer, KA, Zimniak, P, Falany, JL, Iscan, M, Falany, CN

Biochem J 1990
Participants
Input
Output
Participates
as an event of
Catalyst Activity

sulfotransferase activity of SULT2A1 dimer [cytosol]

Physical Entity
SULT2A1 dimer [cytosol] (Homo sapiens)
Activity
sulfotransferase activity (GO:0008146)
Orthologous Events
lithocholate + PAPS => lithocholate sulfate + PAP (Bos taurus)
lithocholate + PAPS => lithocholate sulfate + PAP (Danio rerio)
lithocholate + PAPS => lithocholate sulfate + PAP (Drosophila melanogaster)
lithocholate + PAPS => lithocholate sulfate + PAP (Gallus gallus)
lithocholate + PAPS => lithocholate sulfate + PAP (Mus musculus)
lithocholate + PAPS => lithocholate sulfate + PAP (Rattus norvegicus)
lithocholate + PAPS => lithocholate sulfate + PAP (Sus scrofa)
lithocholate + PAPS => lithocholate sulfate + PAP (Xenopus tropicalis)
Cross References
Rhea
Reviewed
D'Eustachio, P  (2008-05-28)
Created
D'Eustachio, P  (2006-03-09)
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