Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
RAD9B [nucleoplasm]
Stable Identifier
R-HSA-176325
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
G2/M Checkpoints (Homo sapiens)
Activation of ATR in response to replication stress (Homo sapiens)
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
G2/M DNA damage checkpoint (Homo sapiens)
ATR phosphorylates TP53 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
HDR through Homologous Recombination (HRR) (Homo sapiens)
Homologous DNA Pairing and Strand Exchange (Homo sapiens)
Presynaptic phase of homologous DNA pairing and strand exchange (Homo sapiens)
RAD51 binds BRCA2 at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
HDR through Single Strand Annealing (SSA) (Homo sapiens)
Association of RAD51 with RAD52:DNA double-strand break ends (Homo sapiens)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
Association of RAD52 with the RPA complex at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
ERCC1:XPF cleaves flaps generated by SSA (Homo sapiens)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
RAD52 promotes single strand annealing at resected DNA DSBs (Homo sapiens)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
Processing of DNA double-strand break ends (Homo sapiens)
ATR activation at DNA DSBs (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
ATR phosphorylates RPA2 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
Activation of CHEK1 at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
CHEK1 is recruited to resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
Regulation of TP53 Activity (Homo sapiens)
Regulation of TP53 Activity through Phosphorylation (Homo sapiens)
ATR phosphorylates TP53 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD9:HUS1:RAD1 [nucleoplasm] (Homo sapiens)
RAD9 [nucleoplasm] (Homo sapiens)
RAD9B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6WBX8 RAD9B
Gene Names
RAD9B
Chain
chain:1-426
Reference Genes
BioGPS Gene:144715 RAD9B
COSMIC (genes):RAD9B RAD9B
CTD Gene:144715 RAD9B
dbSNP Gene:144715 RAD9B
ENSEMBL:ENSG00000151164 RAD9B
HGNC:21700 RAD9B
KEGG Gene (Homo sapiens):144715 RAD9B
Monarch:144715 RAD9B
NCBI Gene:144715 RAD9B
OMIM:608368 RAD9B
UCSC:Q6WBX8 RAD9B
Reference Transcript
RefSeq:XM_017018878.1 RAD9B
RefSeq:NM_001286533.1 RAD9B
RefSeq:NM_152442.3 RAD9B
RefSeq:XM_011537974.2 RAD9B
RefSeq:NM_001286532.1 RAD9B
RefSeq:NM_001286536.1 RAD9B
RefSeq:NM_001286531.1 RAD9B
RefSeq:XM_017018882.1 RAD9B
RefSeq:NM_001286534.1 RAD9B
RefSeq:NM_001286535.1 RAD9B
Other Identifiers
0000360368
11734408_a_at
11746355_a_at
144715
1553285_s_at
1564688_a_at
16756974
3431584
3431585
3431590
3431591
3431592
3431593
3431595
3431596
3431597
3431598
3431599
3431600
3431602
3431603
3431604
3431605
3431606
40643
64855_at
7958677
A0A024RBN9
A_14_P112705
A_14_P115094
A_23_P333650
A_33_P3361229
B4DX60
B4DYM6
CCDS73527
CH471054
EAW97923
EAW97925
ENSG00000151164
ENSP00000386629
ENSP00000387329
ENST00000409246
ENST00000409246.5
ENST00000409425
ENST00000409425.5
EntrezGene:144715
EntrezGene:RAD9B
GE541541
GO:0000077
GO:0000228
GO:0000278
GO:0003674
GO:0004518
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0006259
GO:0006260
GO:0006281
GO:0006950
GO:0007049
GO:0007165
GO:0008150
GO:0008408
GO:0009058
GO:0030896
GO:0031573
GO:0032991
GO:0034641
GO:0043226
GO:0071479
GO:0090305
GO:1901796
H7BY23
HGNC:21700
HPA040643
Hs2.97794.1.S1_3p_s_at
Hs2.97794.2.S1_3p_s_at
ILMN_1654677
IPR007268
IPR026584
J3KPN7
MIM:608368
NM_001286531
NM_001286532
NM_001286533
NM_001286534
NM_001368051
NM_001368053
NM_001368055
NP_001273460
NP_001273461
NP_001273462
NP_001273463
NP_001354980
NP_001354982
NP_001354984
PF04139
PH_hs_0005337
RAD9B
RAD9B-203
RAD9B-205
TC12000858.hg
UPI00001C098B
XM_017018879
XM_017018880
XM_017018882
XM_024448860
XM_024448861
XP_016874368
XP_016874369
XP_016874371
XP_024304628
XP_024304629
Participant Of
hasMember
RAD9 [nucleoplasm]
Inferred To
RAD9B [nucleoplasm] (Bos taurus)
RAD9B [nucleoplasm] (Caenorhabditis elegans)
RAD9B [nucleoplasm] (Canis familiaris)
RAD9B [nucleoplasm] (Danio rerio)
RAD9B [nucleoplasm] (Dictyostelium discoideum)
RAD9B [nucleoplasm] (Drosophila melanogaster)
RAD9B [nucleoplasm] (Mus musculus)
RAD9B [nucleoplasm] (Rattus norvegicus)
RAD9B [nucleoplasm] (Saccharomyces cerevisiae)
RAD9B [nucleoplasm] (Schizosaccharomyces pombe)
RAD9B [nucleoplasm] (Sus scrofa)
RAD9B [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
XP_016874371.1
,
NP_689655.3
,
NP_001273462.1
,
NP_001273464.1
,
NP_001273460.1
,
NP_001273461.1
,
NP_001273463.1
,
NP_001273465.1
,
XP_016874367.1
,
XP_011536276.1
OpenTargets
ENSG00000151164
GeneCards
Q6WBX8
PRO
Q6WBX8
© 2019
Reactome
