RAD9:HUS1:RAD1

Stable Identifier
R-HSA-176312
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Rad9-Hus1-Rad1 complex, 9-1-1 complex
Locations in the PathwayBrowser
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Summation

The Rad9-Hus1-Rad1 (9-1-1) complex is a ring-shaped heterotrimeric complex. Under genotoxic stress conditions, it can be loaded onto DNA at sites of damage or stalled forks by the Rad17 complex.

Literature References
PubMed ID Title Journal Year
11907025 Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy

Griffith, JD, Lindsey-Boltz, LA, Sancar, A

J Biol Chem 2002
Participants
components
Participant Of
input
output
hasComponent
Inferred To
RAD9:HUS1:RAD1 [nucleoplasm] (Bos taurus)
RAD9:HUS1:RAD1 [nucleoplasm] (Caenorhabditis elegans)
RAD9:HUS1:RAD1 [nucleoplasm] (Canis familiaris)
RAD9:HUS1:RAD1 [nucleoplasm] (Danio rerio)
RAD9:HUS1:RAD1 [nucleoplasm] (Dictyostelium discoideum)
RAD9:HUS1:RAD1 [nucleoplasm] (Drosophila melanogaster)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Mus musculus)
RAD9:HUS1:RAD1 [nucleoplasm] (Rattus norvegicus)
RAD9:HUS1:RAD1 [nucleoplasm] (Sus scrofa)
RAD9:HUS1:RAD1 [nucleoplasm] (Taeniopygia guttata)
RAD9:HUS1:RAD1 [nucleoplasm] (Xenopus tropicalis)
Cross References
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