RAD9:HUS1:RAD1 [nucleoplasm]

Stable Identifier
R-HSA-176312
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Rad9-Hus1-Rad1 complex, 9-1-1 complex
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General

The Rad9-Hus1-Rad1 (9-1-1) complex is a ring-shaped heterotrimeric complex. Under genotoxic stress conditions, it can be loaded onto DNA at sites of damage or stalled forks by the Rad17 complex.

Literature References
PubMed ID Title Journal Year
11907025 Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy

Lindsey-Boltz, LA, Sancar, A, Griffith, JD

J Biol Chem 2002
Participants
components
Participates
as a component of
as an input of
as an output of
Inferred To
RAD9:HUS1:RAD1 [nucleoplasm] (Bos taurus)
RAD9:HUS1:RAD1 [nucleoplasm] (Caenorhabditis elegans)
RAD9:HUS1:RAD1 [nucleoplasm] (Canis familiaris)
RAD9:HUS1:RAD1 [nucleoplasm] (Danio rerio)
RAD9:HUS1:RAD1 [nucleoplasm] (Dictyostelium discoideum)
RAD9:HUS1:RAD1 [nucleoplasm] (Drosophila melanogaster)
RAD9:HUS1:RAD1 [nucleoplasm] (Gallus gallus)
RAD9:HUS1:RAD1 [nucleoplasm] (Mus musculus)
RAD9:HUS1:RAD1 [nucleoplasm] (Rattus norvegicus)
RAD9:HUS1:RAD1 [nucleoplasm] (Saccharomyces cerevisiae)
RAD9:HUS1:RAD1 [nucleoplasm] (Schizosaccharomyces pombe)
RAD9:HUS1:RAD1 [nucleoplasm] (Sus scrofa)
RAD9:HUS1:RAD1 [nucleoplasm] (Xenopus tropicalis)
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