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GSTP1 [cytosol]
Stable Identifier
R-HSA-176051
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Glutathione S-transferase pi 1
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Detoxification of Reactive Oxygen Species (Homo sapiens)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
PRDX6:GSTP1 [cytosol] (Homo sapiens)
GSTP1 [cytosol] (Homo sapiens)
Drug ADME (Homo sapiens)
Paracetamol ADME (Homo sapiens)
GSTs transfer GSH to NAPQI to form APAP-SG (Homo sapiens)
GSTM1,P1,T1 dimers [cytosol] (Homo sapiens)
GSTP1 dimer [cytosol] (Homo sapiens)
GSTP1 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Glutathione conjugation (Homo sapiens)
GST dimers conjugate GSH with cytosolic substrates (Homo sapiens)
GST dimers [cytosol] (Homo sapiens)
GSTP1 dimer [cytosol] (Homo sapiens)
GSTP1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09211 GSTP1
Gene Names
GSTP1, FAEES3, GST3
Chain
initiator methionine:, chain:2-210
Reference Genes
BioGPS Gene:2950 GSTP1
COSMIC (genes):GSTP1 GSTP1
CTD Gene:2950 GSTP1
dbSNP Gene:2950 GSTP1
ENSEMBL:ENSG00000084207 GSTP1
ENSEMBL_homo_sapiens_GENE:ENSG00000084207.18 GSTP1
HGNC:4638 GSTP1
KEGG Gene (Homo sapiens):2950 GSTP1
Monarch:2950 GSTP1
NCBI Gene:2950 GSTP1
OMIM:134660 GSTP1
Reference Transcript
RefSeq:NM_000852.3 GSTP1
Other Identifiers
11715344_at
16727919
200824_3p_at
200824_PM_at
200824_at
2950
3337176
3337178
3337180
3337182
3337185
3337187
3337188
3337191
3337192
3337193
33396_at
7941936
829_s_at
A_14_P107175
A_23_P202658
GO:0000302
GO:0002674
GO:0003824
GO:0004364
GO:0004602
GO:0005504
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005739
GO:0005829
GO:0006469
GO:0006575
GO:0006629
GO:0006693
GO:0006749
GO:0006790
GO:0006805
GO:0006954
GO:0007417
GO:0008289
GO:0008432
GO:0009890
GO:0010804
GO:0012501
GO:0016209
GO:0016491
GO:0016740
GO:0019207
GO:0023052
GO:0031410
GO:0031982
GO:0032691
GO:0032720
GO:0032872
GO:0032873
GO:0032930
GO:0034774
GO:0035726
GO:0035730
GO:0035731
GO:0035732
GO:0036211
GO:0043066
GO:0043124
GO:0043226
GO:0043407
GO:0043409
GO:0043508
GO:0043651
GO:0048147
GO:0048856
GO:0051122
GO:0051771
GO:0070026
GO:0070062
GO:0070372
GO:0070373
GO:0070664
GO:0071222
GO:0071638
GO:0097057
GO:0098754
GO:0098772
GO:0098869
GO:1901687
GO:1904813
GO:2001237
HMNXSV003039809
ILMN_1679809
M24485_s_at
PH_hs_0019546
PH_hs_0035926
TC11000694.hg
U21689_at
g6552334_3p_at
g6552334_3p_s_at
g6552334_3p_x_at
Participates
as a component of
GSTP1 dimer [cytosol] (Homo sapiens)
PRDX6:GSTP1 [cytosol] (Homo sapiens)
Other forms of this molecule
GSTP1 [secretory granule lumen]
GSTP1 [extracellular region]
GSTP1 [ficolin-1-rich granule lumen]
Inferred To
LOC100739163 [cytosol]
(Sus scrofa)
GSTP1 [cytosol]
(Bos taurus)
GSTP1 [cytosol]
(Caenorhabditis elegans)
GSTP1 [cytosol]
(Canis familiaris)
GSTP1 [cytosol]
(Dictyostelium discoideum)
GSTP1 [cytosol]
(Mus musculus)
GSTP1 [cytosol]
(Plasmodium falciparum)
GSTP1 [cytosol]
(Rattus norvegicus)
Homologues of GSTP1 [cytosol]
(Bos taurus)
Homologues of GSTP1 [cytosol]
(Canis familiaris)
Homologues of GSTP1 [cytosol]
(Dictyostelium discoideum)
Homologues of GSTP1 [cytosol]
(Mus musculus)
LOC101730710 [cytosol]
(Xenopus tropicalis)
gstp1.2 [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_000843.1
ZINC - World Drugs
GSTP1_HUMAN
OpenTargets
ENSG00000084207
ZINC - FDA approved
GSTP1_HUMAN
ZINC - Substances
GSTP1_HUMAN
ZINC - Biogenic
GSTP1_HUMAN
ZINC target
P09211
PRO
P09211
PDB
3HJM
,
4PGT
,
11GS
,
5DDL
,
1EOG
,
3HJO
,
6AP9
,
3CSJ
,
1KBN
,
6GSS
,
3KMN
,
12GS
,
9GSS
,
3KMO
,
2GSS
,
2J9H
,
20GS
,
7XBA
,
5GSS
,
3HKR
,
5JCW
,
3GSS
,
8GSS
,
5J41
,
3GUS
,
22GS
,
3N9J
,
5DCG
,
18GS
,
2PGT
,
3KM6
,
1MD4
,
1AQW
,
5DJL
,
10GS
,
1MD3
,
2A2S
,
1AQV
,
5L6X
,
5DJM
,
3DD3
,
14GS
,
1GSS
,
1LBK
,
13GS
,
1EOH
,
1PGT
,
1PX7
,
1PX6
,
1AQX
,
6Y1E
,
17GS
,
16GS
,
4GSS
,
3CSH
,
3CSI
,
6LLX
,
7GSS
,
2A2R
,
3DGQ
,
7BIA
,
5DAK
,
19GS
,
5X79
,
3PGT
,
3IE3
,
5DAL
,
1ZGN
ZINC - Metabolites
GSTP1_HUMAN
IntEnz
2.5.1.18
HPA
ENSG00000084207-GSTP1
GeneCards
P09211
Ensembl
ENSP00000381607
,
ENSG00000084207
,
ENST00000398606
Pharos - Targets
P09211
ZINC - Predictions - Purchasable
GSTP1_HUMAN
HMDB Protein
HMDBP00834
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12933 TRAF2
5
TRAF2 [nucleoplasm]
(R-HSA-8862199)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
TRAF2 [cytosol]
(R-HSA-66370)
0.68
5
UniProt:P22735 TGM1
3
TGM1 [cytosol]
(R-HSA-6813756)
TGM1 [cornified envelope]
(R-HSA-8847706)
TGM1 [plasma membrane]
(R-HSA-6813757)
0.556
3
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.556
3
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
12
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