Reactome | GSTA1 [cytosol]

GSTA1 [cytosol]

Stable Identifier

R-HSA-176050

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Glutathione S-transferase alpha 1

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Cellular response to chemical stress (Homo sapiens)
    - KEAP1-NFE2L2 pathway (Homo sapiens)
      - Nuclear events mediated by NFE2L2 (Homo sapiens)
        
        NFE2L2 regulating anti-oxidant/detoxification enzymes (Homo sapiens)
        
        AcK-NFE2L2-dependent GSTA1 gene expression (Homo sapiens)
        
        GSTA1 dimer [cytosol] (Homo sapiens)
        
        GSTA1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P08263 GSTA1

Gene Names

GSTA1

Chain

chain:1-222, initiator methionine:, chain:2-222

Reference Genes

BioGPS Gene:2938 GSTA1

COSMIC (genes):GSTA1 GSTA1

CTD Gene:2938 GSTA1

dbSNP Gene:2938 GSTA1

ENSEMBL:ENSG00000243955 GSTA1

HGNC:4626 GSTA1

KEGG:hsa:2938 GSTA1

Monarch:2938 GSTA1

NCBI Gene:2938 GSTA1

OMIM:138359 GSTA1

UCSC:P08263 GSTA1

Reference Transcript

RefSeq:NM_145740.4 GSTA1

Other Identifiers

11724219_x_at

1260_s_at

17020069

203924_PM_at

203924_at

2938

2957329

2957335

2957336

2957352

2957355

2957356

2957357

2957358

2957359

2957360

2957365

2957366

2957368

2957369

2957370

2957371

2957373

2957376

2957385

2957391

2957398

2957416

2957419

58023_at

8127072

A_23_P214300

GE79099

GO:0003824

GO:0004364

GO:0004601

GO:0004602

GO:0004769

GO:0005504

GO:0005515

GO:0005737

GO:0005829

GO:0006575

GO:0006629

GO:0006693

GO:0006749

GO:0006790

GO:0006805

GO:0008289

GO:0016209

GO:0016491

GO:0016740

GO:0016853

GO:0030154

GO:0030855

GO:0043226

GO:0043651

GO:0070062

GO:0098754

GO:0098869

GO:1901687

HMNXSV003014071

ILMN_1701831

ILMN_1894117

ILMN_2113470

TC06001803.hg

X65727_cds2_s_at

g4504170_3p_at

Participates

as a component of

as a member of

GSTA1, FABP1 [cytosol] (Homo sapiens)

Inferred To

gsta.1 [cytosol] (Danio rerio)

Gsta13 [cytosol] (Mus musculus)

LOC474938 [cytosol] (Canis familiaris)

LOC100526118 [cytosol] (Sus scrofa)

Gsta5 [cytosol] (Mus musculus)

LOC100496158 [cytosol] (Xenopus tropicalis)

Homologues of GSTA1 [cytosol] (Bos taurus)

Homologues of GSTA1 [cytosol] (Dictyostelium discoideum)

Homologues of GSTA1 [cytosol] (Mus musculus)

Homologues of GSTA1 [cytosol] (Rattus norvegicus)

Homologues of GSTA1 [cytosol] (Sus scrofa)

Homologues of GSTA1 [cytosol] (Xenopus tropicalis)

gsta4 [cytosol] (Xenopus tropicalis)

GSTA1 [cytosol] (Bos taurus)

GSTA1 [cytosol] (Dictyostelium discoideum)

GSTA1 [cytosol] (Mus musculus)

GSTA1 [cytosol] (Plasmodium falciparum)

GSTA1 [cytosol] (Rattus norvegicus)

GSTA1 [cytosol] (Sus scrofa)

Cross References

OpenTargets

ENSG00000243955

ENSEMBL

ENSP00000335620, ENST00000334575, ENSG00000243955

ZINC - FDA approved

GSTA1_HUMAN

ZINC - Substances

GSTA1_HUMAN

ZINC - Biogenic

GSTA1_HUMAN

ZINC target

P08263

PRO

P08263

PDB

1PL2, 1PL1, 2R3X, 3U6V, 5JCU, 1K3Y, 3KTL, 3I6A, 1GSD, 1K3O, 1PKW, 1K3L, 2R6K, 1PKZ, 3ZFB, 6ATR, 6ATQ, 3IK9, 3I69, 7BIB, 8BHE, 3L0H, 1USB, 3ZFL, 7BIC, 1XWG, 1GSF, 6YAW, 6ATO, 4HJ2, 1YDK, 1GUH, 6ATP, 1GSE, 8BHC, 3Q74, 5LD0, 1LBK, 5LCZ

ZINC - Metabolites

GSTA1_HUMAN

IntEnz

2.5.1.18

HPA

ENSG00000243955-GSTA1

GeneCards

GSTA1

Pharos - Targets

P08263

ZINC - Predictions - Purchasable

GSTA1_HUMAN

HMDB Protein

HMDBP00816