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CCR5, CXCR4 [plasma membrane]
Stable Identifier
R-HSA-175536
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Early Phase of HIV Life Cycle (Homo sapiens)
Binding and entry of HIV virion (Homo sapiens)
CD4:gp120 binds to chemokine co-receptor CCR5/CXCR4 (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Virion with CD4:gp120 bound to CCR5/CXCR4 [extracellular region] (Homo sapiens)
CD4:Env gp120:CCR5,CXCR4:complex [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Conformational changes in gp120 exposes gp41 (Homo sapiens)
Virion with CD4:gp120 bound to CCR5/CXCR4 [extracellular region] (Homo sapiens)
CD4:Env gp120:CCR5,CXCR4:complex [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Virion with gp41 exposed [extracellular region] (Homo sapiens)
CCR5/CXCR4:CD4:Env gp120 (second conformation change) complex [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Fusion of viral membrane with host cell membrane (Homo sapiens)
CD4:Env gp120/gp41 hairpin complex:CCR5/CXCR4 [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Virion with gp41 forming hairpin structure [extracellular region] (Homo sapiens)
CD4:Env gp120/gp41 hairpin complex:CCR5/CXCR4 [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Fusogenic activation of gp41 (Homo sapiens)
Virion with fusogenically activated gp41 [extracellular region] (Homo sapiens)
CD4:Env gp120/gp41 fusion peptide complex:CCR5 [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Virion with gp41 exposed [extracellular region] (Homo sapiens)
CCR5/CXCR4:CD4:Env gp120 (second conformation change) complex [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Insertion of gp41 fusion peptide into the target membrane (Homo sapiens)
Virion with fusogenically activated gp41 [extracellular region] (Homo sapiens)
CD4:Env gp120/gp41 fusion peptide complex:CCR5 [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Virion with gp41 fusion peptide in insertion complex [extracellular region] (Homo sapiens)
CD4:Env gp120/gp41insertion complex:CCR5/CXCR4 [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
N and C terminal heptad repeat helices of gp41 form six-helix bundle (Homo sapiens)
Virion with gp41 forming hairpin structure [extracellular region] (Homo sapiens)
CD4:Env gp120/gp41 hairpin complex:CCR5/CXCR4 [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Virion with gp41 fusion peptide in insertion complex [extracellular region] (Homo sapiens)
CD4:Env gp120/gp41insertion complex:CCR5/CXCR4 [plasma membrane] (Homo sapiens)
CCR5, CXCR4 [plasma membrane] (Homo sapiens)
Participants
members
CCR5 [plasma membrane]
(Homo sapiens)
CXCR4 [plasma membrane]
(Homo sapiens)
Participates
as a component of
CD4:Env gp120/gp41 hairpin complex:CCR5/CXCR4 [plasma membrane] (Homo sapiens)
CD4:Env gp120/gp41insertion complex:CCR5/CXCR4 [plasma membrane] (Homo sapiens)
CD4:Env gp120:CCR5,CXCR4:complex [plasma membrane] (Homo sapiens)
CD4:Env gp120/gp41 fusion peptide complex:CCR5 [plasma membrane] (Homo sapiens)
CCR5/CXCR4:CD4:Env gp120 (second conformation change) complex [plasma membrane] (Homo sapiens)
as an input of
CD4:gp120 binds to chemokine co-receptor CCR5/CXCR4 (Homo sapiens)
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