Virion assembly packages all the components required for infectivity. These steps include two copies of the positive sense genomic viral RNA, cellular tRNALys, the viral envelope (Env) protein, the Gag polyprotein, and the three viral enzymes: protease (PR), reverse transcriptase (RT), and integrase (IN). The viral enzymes are packaged as domains within the Gag-Pro-Pol polyprotein.
Varmus, HE, Hughes, SH, Coffin, JM
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