NAT1 acetylation

Stable Identifier
R-HSA-174963
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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NAT1 acetylation
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Typical NAT 1 substrates were chosen as examples. They are sulfanilamide, 4-aminosalicylate, 4-aminobenzoate and N-hydroxy 4-aminobiphenyl (Hong et al. 2017).
Literature References
PubMed ID Title Journal Year
28380339 Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB

Cai, Y, Wang, H, Ding, H, Han, A, Hong, H, Zhang, S

Structure 2017
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Output
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as an event of
Catalyst Activity

arylamine N-acetyltransferase activity of AcC-NAT1 [cytosol]

Physical Entity
AcC-NAT1 [cytosol] (Homo sapiens)
Activity
arylamine N-acetyltransferase activity (GO:0004060)
Orthologous Events
NAT1 acetylation (Bos taurus)
NAT1 acetylation (Danio rerio)
NAT1 acetylation (Gallus gallus)
NAT1 acetylation (Mus musculus)
NAT1 acetylation (Rattus norvegicus)
NAT1 acetylation (Sus scrofa)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2006-02-23)
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